Understanding the Chemical Properties of 5-Bromo-2-fluorobenzaldehyde (CAS 93777-26-5)
The efficacy of any chemical intermediate hinges on its inherent chemical properties, which dictate its behavior in various synthetic pathways. 5-Bromo-2-fluorobenzaldehyde, identified by its CAS number 93777-26-5, is a compound whose structure and properties make it a highly sought-after organic synthesis building block. NINGBO INNO PHARMCHEM CO.,LTD., a reputable manufacturer in China, ensures the provision of this chemical with well-defined characteristics, crucial for its intended applications.
At its core, 5-Bromo-2-fluorobenzaldehyde is an aromatic aldehyde featuring a benzene ring substituted with a bromine atom at the 5-position and a fluorine atom at the 2-position. The molecular formula is C7H4BrFO, with a molecular weight of approximately 203.01 g/mol. This specific arrangement of substituents significantly influences its reactivity. The electronegativity of the fluorine atom and the electron-withdrawing nature of both halogens can activate the aromatic ring for certain reactions, while the bromine atom serves as an excellent leaving group or a site for metal-catalyzed cross-coupling reactions. The aldehyde group itself is highly reactive, readily participating in nucleophilic addition, oxidation, and reduction reactions.
These chemical properties make it an invaluable pharmaceutical intermediate. For instance, the aldehyde group can be easily transformed into alcohols, carboxylic acids, or imines, which are common functional groups found in many drug molecules. The halogens can be further functionalized using reactions like the Suzuki, Heck, or Sonogashira couplings, allowing for the introduction of diverse carbon-based substituents. This ability to participate in a wide range of transformations makes it a versatile component for building complex molecular scaffolds. When you buy this compound from a trusted supplier like NINGBO INNO PHARMCHEM CO.,LTD., you are assured of its consistent chemical profile.
The physical properties also play a role in its handling and application. Typically appearing as an off-white crystalline powder, it has a melting point range of 58-62°C, indicating it is a solid at room temperature. Understanding these properties is key for storage and processing. The price of 5-Bromo-2-fluorobenzaldehyde is also a consideration for large-scale industrial use, and procuring it from a competitive manufacturer in China ensures cost-effectiveness.
In summary, the chemical properties of 5-Bromo-2-fluorobenzaldehyde, including its reactive functional groups and strategic halogen placement, establish it as a cornerstone organic synthesis intermediate. Its well-defined characteristics, supported by manufacturers like NINGBO INNO PHARMCHEM CO.,LTD., enable its extensive use in pharmaceutical development and fine chemical production, solidifying its position as a vital building block in modern chemistry.
At its core, 5-Bromo-2-fluorobenzaldehyde is an aromatic aldehyde featuring a benzene ring substituted with a bromine atom at the 5-position and a fluorine atom at the 2-position. The molecular formula is C7H4BrFO, with a molecular weight of approximately 203.01 g/mol. This specific arrangement of substituents significantly influences its reactivity. The electronegativity of the fluorine atom and the electron-withdrawing nature of both halogens can activate the aromatic ring for certain reactions, while the bromine atom serves as an excellent leaving group or a site for metal-catalyzed cross-coupling reactions. The aldehyde group itself is highly reactive, readily participating in nucleophilic addition, oxidation, and reduction reactions.
These chemical properties make it an invaluable pharmaceutical intermediate. For instance, the aldehyde group can be easily transformed into alcohols, carboxylic acids, or imines, which are common functional groups found in many drug molecules. The halogens can be further functionalized using reactions like the Suzuki, Heck, or Sonogashira couplings, allowing for the introduction of diverse carbon-based substituents. This ability to participate in a wide range of transformations makes it a versatile component for building complex molecular scaffolds. When you buy this compound from a trusted supplier like NINGBO INNO PHARMCHEM CO.,LTD., you are assured of its consistent chemical profile.
The physical properties also play a role in its handling and application. Typically appearing as an off-white crystalline powder, it has a melting point range of 58-62°C, indicating it is a solid at room temperature. Understanding these properties is key for storage and processing. The price of 5-Bromo-2-fluorobenzaldehyde is also a consideration for large-scale industrial use, and procuring it from a competitive manufacturer in China ensures cost-effectiveness.
In summary, the chemical properties of 5-Bromo-2-fluorobenzaldehyde, including its reactive functional groups and strategic halogen placement, establish it as a cornerstone organic synthesis intermediate. Its well-defined characteristics, supported by manufacturers like NINGBO INNO PHARMCHEM CO.,LTD., enable its extensive use in pharmaceutical development and fine chemical production, solidifying its position as a vital building block in modern chemistry.
Perspectives & Insights
Bio Analyst 88
“This specific arrangement of substituents significantly influences its reactivity.”
Nano Seeker Pro
“The electronegativity of the fluorine atom and the electron-withdrawing nature of both halogens can activate the aromatic ring for certain reactions, while the bromine atom serves as an excellent leaving group or a site for metal-catalyzed cross-coupling reactions.”
Data Reader 7
“The aldehyde group itself is highly reactive, readily participating in nucleophilic addition, oxidation, and reduction reactions.”