For R&D scientists and product formulators in the pharmaceutical and fine chemical sectors, a thorough understanding of intermediate compounds is key to innovation. (2R,5R)-5-Hydroxy-1,3-oxathiolane-2-carboxylic acid (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester, identified by its CAS number 147126-62-3, is a prime example of such a critical molecule. This chemically complex ester plays an indispensable role as an intermediate in the synthesis of lamivudine, a cornerstone medication in antiviral therapy.

Delving into the chemical structure reveals a chiral molecule with specific stereochemistry that is vital for its function. The compound features a 1,3-oxathiolane ring system with hydroxyl and ester functionalities, along with a bulky menthyl ester group derived from (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexanol. This precise stereochemical arrangement is paramount, as it directly dictates the enantiomeric purity and biological activity of the final lamivudine product. Manufacturers offering this compound typically highlight its high purity and specific isomeric form, crucial for pharmaceutical applications. Buyers seeking this material often search for terms like 'high purity 147126-62-3' or 'chiral pharmaceutical intermediate'.'

The synthesis of CAS 147126-62-3 often involves multi-step organic synthesis routes. While specific proprietary methods vary among manufacturers, common approaches might involve the esterification of a suitably functionalized oxathiolane carboxylic acid derivative with the menthol moiety. The development of efficient and stereoselective synthesis pathways is a testament to the advancements in organic chemistry. For those looking to purchase, understanding these synthetic complexities helps in evaluating the reliability and expertise of a potential supplier. When considering bulk orders, inquiring about the manufacturing process and quality control measures from a Chinese supplier can provide valuable assurance.

The primary application of this ester is its role as a key intermediate for lamivudine. Lamivudine is a nucleoside reverse transcriptase inhibitor (NRTI) and is a critical component in antiretroviral therapy for HIV and treatment for chronic Hepatitis B. The demand for such life-saving medications drives the need for a stable and cost-effective supply of their precursors. Therefore, finding a reputable manufacturer that can supply (2R,5R)-5-Hydroxy-1,3-oxathiolane-2-carboxylic acid (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester at a competitive price point is a strategic imperative for pharmaceutical companies.

In summary, for professionals engaged in pharmaceutical development and manufacturing, grasping the chemical significance and synthetic routes of CAS 147126-62-3 is essential. Its role as a lamivudine intermediate underscores its importance in modern medicine. By partnering with experienced suppliers and manufacturers who can guarantee high purity and consistent supply, your organization can contribute effectively to the global healthcare landscape.