Understanding the Properties and Applications of 2-[4-(Trifluoromethyl)phenyl]pyridine
In the dynamic world of chemical synthesis, understanding the properties of specific molecules is paramount for their effective utilization. 2-[4-(Trifluoromethyl)phenyl]pyridine, identified by CAS number 203065-88-7, is a sophisticated organic compound that has garnered significant attention due to its unique structural features and broad applicability, particularly in the pharmaceutical and materials science sectors.
Chemically, this compound boasts a molecular formula of C12H8F3N and a molecular weight of 223.19400 g/mol. Its physical characteristics include a melting point typically ranging from 74.0 to 78.0 °C, classifying it as a solid at room temperature. The compound exhibits a boiling point of 266.362 ºC at atmospheric pressure (760 mmHg) and a density of 1.23 g/cm³. Its appearance is noted as white to yellow solid, indicating potential variations based on purity or minor impurities, which is a common characteristic for such complex organic molecules. The refractive index is listed as 1.506.
The presence of the trifluoromethyl (-CF3) group is a key feature, imparting distinct electronic and lipophilic properties to the molecule. This group is known to enhance the metabolic stability of drug candidates, increase cell membrane permeability, and improve binding interactions with biological targets. Consequently, 2-[4-(trifluoromethyl)phenyl]pyridine serves as a valuable building block in the synthesis of active pharmaceutical ingredients (APIs) and advanced intermediates.
Beyond pharmaceuticals, this versatile compound finds applications in material science. Fluorinated organic compounds are often incorporated into organic electronic materials, such as those used in OLEDs (Organic Light-Emitting Diodes) and organic photovoltaics, to tune their electronic properties, improve charge transport, and enhance device longevity. Researchers looking to develop novel functional materials may find 2-[4-(trifluoromethyl)phenyl]pyridine to be a useful starting point.
For chemists and researchers involved in these fields, sourcing this compound reliably is essential. Those looking to buy 2-[4-(trifluoromethyl)phenyl]pyridine will be interested in its availability from reputable chemical suppliers. The ability to secure high purity material (often advertised as 98+% purity) is critical for reproducible results in complex syntheses. When considering the price, it is often beneficial to consult with manufacturers directly, especially for bulk orders. A dedicated supplier that specializes in heterocyclic chemistry can provide not only the product but also valuable technical support.
In summary, 2-[4-(trifluoromethyl)phenyl]pyridine is a powerful tool in the modern chemist's arsenal. Its physicochemical properties, driven by its unique structure, make it a highly sought-after intermediate for drug discovery, agrochemical development, and the creation of advanced materials. Ensuring access to quality material from reliable sources is key to unlocking its full potential.
Perspectives & Insights
Nano Explorer 01
“Chemically, this compound boasts a molecular formula of C12H8F3N and a molecular weight of 223.”
Data Catalyst One
“Its appearance is noted as white to yellow solid, indicating potential variations based on purity or minor impurities, which is a common characteristic for such complex organic molecules.”
Chem Thinker Labs
“The presence of the trifluoromethyl (-CF3) group is a key feature, imparting distinct electronic and lipophilic properties to the molecule.”