Understanding the Properties and Applications of Diethyl 2-[4-(chlorobenzoyl)amino]Malonate
Diethyl 2-[4-(chlorobenzoyl)amino]Malonate, bearing the CAS number 81918-01-6, is a significant chemical compound primarily recognized for its utility as a pharmaceutical intermediate. Its well-defined chemical structure and high purity make it an indispensable component in various synthesis processes, particularly within the pharmaceutical industry.
The compound's physical characteristics typically include a white or off-white powder appearance, indicative of its refined state. Chemically, it is characterized by its molecular formula C14H16ClNO5 and a molecular weight of approximately 313.73 g/mol. These properties, along with its high purity (often exceeding 99.5%), are fundamental to its successful application in sensitive chemical reactions.
The primary application of Diethyl 2-[4-(chlorobenzoyl)amino]Malonate is as a pharmaceutical intermediate. It serves as a crucial building block in the synthesis of more complex drug molecules. Specifically, its role in the preparation of Rebamipide, an anti-ulcerative medication, and its use in the creation of indole-based PPARγ ligands highlight its therapeutic relevance. Researchers often search for terms like Diethyl 2-[4-(chlorobenzoyl)amino]Malonate uses to understand its potential in their specific research areas.
For those looking to buy Diethyl 2-[4-(chlorobenzoyl)amino]Malonate, understanding the market dynamics is beneficial. The availability of this intermediate is often tied to the broader pharmaceutical manufacturing landscape. Reliable suppliers, such as NINGBO INNO PHARMCHEM CO.,LTD., ensure consistent quality and availability, typically offering the product in 25kg drums to meet industrial demands. The Diethyl 2-[4-(chlorobenzoyl)amino]Malonate price is influenced by factors such as purity, order volume, and global supply chain conditions.
The chemical structure itself, featuring a malonate ester coupled with a chlorobenzoyl-protected amine, lends itself to diverse synthetic transformations. This makes Diethyl 2-[4-(chlorobenzoyl)amino]Malonate a versatile intermediate for medicinal chemists aiming to construct novel molecular scaffolds with potential biological activity.
In conclusion, Diethyl 2-[4-(chlorobenzoyl)amino]Malonate is a critical fine chemical with significant implications for pharmaceutical research and development. Its specific properties and applications make it a sought-after intermediate, and understanding its market and sourcing options is vital for efficient project execution.
Perspectives & Insights
Core Pioneer 24
“The chemical structure itself, featuring a malonate ester coupled with a chlorobenzoyl-protected amine, lends itself to diverse synthetic transformations.”
Silicon Explorer X
“This makes Diethyl 2-[4-(chlorobenzoyl)amino]Malonate a versatile intermediate for medicinal chemists aiming to construct novel molecular scaffolds with potential biological activity.”
Quantum Catalyst AI
“In conclusion, Diethyl 2-[4-(chlorobenzoyl)amino]Malonate is a critical fine chemical with significant implications for pharmaceutical research and development.”