For professionals in the chemical and pharmaceutical industries, a thorough understanding of the properties and sourcing of key intermediates is vital for project success. 5-Bromo-2-chloro-3-fluoropyridine (CAS: 831203-13-5) is one such compound that offers significant utility due to its specific chemical characteristics. This article aims to provide detailed insights into its physical and chemical properties, and to guide procurement managers on how to effectively purchase this valuable intermediate from manufacturers and suppliers.

Physicochemical Characteristics of 5-Bromo-2-chloro-3-fluoropyridine

5-Bromo-2-chloro-3-fluoropyridine is a complex organic molecule characterized by its halogenated pyridine structure. Its appearance is typically described as a white to off-white powder or solid. This physical state is consistent with its melting point, which is generally reported in the range of 50-52°C. This relatively low melting point means it can be easily handled and processed in various synthetic applications, and it also provides a quick indicator of purity. A higher or broader melting point range might suggest the presence of impurities.

The molecular formula of this compound is C5H2BrClFN, with a molecular weight of approximately 210.43 g/mol. The density is around 1.829 g/cm³, which is higher than water, reflecting the presence of heavy halogen atoms. Its boiling point is predicted to be around 195.3°C at standard atmospheric pressure, although precise experimental values can vary. These properties collectively define its behavior in chemical reactions and its storage requirements.

From a safety perspective, 5-Bromo-2-chloro-3-fluoropyridine is classified as an irritant (Hazard Codes Xi, Xn). It carries hazard statements such as H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Precautionary statements like P261 (Avoid breathing dust/fume/gas/mist/vapours/spray) and P280a (Wear protective gloves/protective clothing/eye protection/face protection) are essential for safe handling. Understanding these safety parameters is crucial for laboratory personnel and anyone involved in its handling and transport.

Procurement Strategies for 5-Bromo-2-chloro-3-fluoropyridine

When seeking to purchase 5-Bromo-2-chloro-3-fluoropyridine, understanding the global supplier landscape is key. Manufacturers, particularly those based in China, often offer competitive pricing for this specialty chemical. For R&D purposes, smaller quantities might be sufficient, and a direct inquiry for price can be made to various suppliers. However, for larger-scale projects or ongoing production, negotiating bulk purchase agreements is advisable.

Procurement managers should prioritize suppliers that can guarantee high purity (often >98% GC) and provide comprehensive analytical data. When considering the CAS 831203-13-5 price, it's important to balance cost with reliability. A supplier with a strong reputation for quality control, consistent product availability, and efficient logistics is invaluable. Requesting free samples can be a good initial step to verify product quality before committing to larger orders.

Furthermore, establishing clear communication channels with potential manufacturers is vital. Understanding their production capacity, lead times, and ability to meet specific packaging requirements can streamline the procurement process. Ultimately, a strategic approach to sourcing this chemical intermediate ensures that your projects benefit from a reliable supply of a high-quality material, facilitating successful outcomes in synthesis and product development.

In conclusion, 5-Bromo-2-chloro-3-fluoropyridine's defined physical and chemical properties, coupled with its reactivity, make it a sought-after intermediate. By employing informed procurement strategies, businesses can secure this essential compound, driving forward their research and manufacturing objectives.