Understanding the Properties of 3-Iodo-6-Nitro-1-(Oxan-2-yl)indazole in Chemical Synthesis
The efficacy of any chemical synthesis, particularly in the pharmaceutical sector, is deeply rooted in the properties of the raw materials and intermediates used. For 3-Iodo-6-Nitro-1-(Oxan-2-yl)indazole (CAS: 886230-74-6), a critical component in the synthesis pathway of the anti-cancer drug Axitinib, understanding its physical and chemical characteristics is paramount. This compound, often sought by those looking for Axitinib synthesis intermediates, exemplifies the precision required in modern chemical manufacturing.
Physically, 3-Iodo-6-Nitro-1-(Oxan-2-yl)indazole is described as an off-white to white crystalline powder. This appearance is indicative of its controlled synthesis and purification processes. Its molecular formula, C12H12IN3O3, and a molecular weight of 373.14600 provide chemists with essential data points for stoichiometric calculations in their synthetic routes. The physical state as a powder facilitates handling and integration into various reaction setups, making it a practical choice for bulk chemical synthesis.
Chemically, the compound exhibits notable stability, with a reported boiling point of 504.111ºC and a flash point of 258.678ºC. These figures suggest a resilience to thermal stress, a valuable trait in chemical processes that may involve elevated temperatures. Its density is recorded at 2.014 g/cm³, providing further insight into its physical nature. The presence of the iodine atom and the nitro group within its indazole core are key to its reactivity, enabling it to participate effectively in subsequent coupling and functionalization reactions, crucial steps in producing complex APIs like Axitinib.
As a leading pharmaceutical intermediate manufacturer in China, NINGBO INNO PHARMCHEM CO.,LTD. places immense emphasis on maintaining these properties through rigorous quality control. Ensuring that the 3-Iodo-6-Nitro-1-(Oxan-2-yl)indazole supplied meets the specified standards is vital for the success of our clients' syntheses. Whether you are researching new drug candidates or scaling up production, understanding these properties helps in planning and executing efficient chemical synthesis, reinforcing our role as a reliable fine chemical supplier.
Physically, 3-Iodo-6-Nitro-1-(Oxan-2-yl)indazole is described as an off-white to white crystalline powder. This appearance is indicative of its controlled synthesis and purification processes. Its molecular formula, C12H12IN3O3, and a molecular weight of 373.14600 provide chemists with essential data points for stoichiometric calculations in their synthetic routes. The physical state as a powder facilitates handling and integration into various reaction setups, making it a practical choice for bulk chemical synthesis.
Chemically, the compound exhibits notable stability, with a reported boiling point of 504.111ºC and a flash point of 258.678ºC. These figures suggest a resilience to thermal stress, a valuable trait in chemical processes that may involve elevated temperatures. Its density is recorded at 2.014 g/cm³, providing further insight into its physical nature. The presence of the iodine atom and the nitro group within its indazole core are key to its reactivity, enabling it to participate effectively in subsequent coupling and functionalization reactions, crucial steps in producing complex APIs like Axitinib.
As a leading pharmaceutical intermediate manufacturer in China, NINGBO INNO PHARMCHEM CO.,LTD. places immense emphasis on maintaining these properties through rigorous quality control. Ensuring that the 3-Iodo-6-Nitro-1-(Oxan-2-yl)indazole supplied meets the specified standards is vital for the success of our clients' syntheses. Whether you are researching new drug candidates or scaling up production, understanding these properties helps in planning and executing efficient chemical synthesis, reinforcing our role as a reliable fine chemical supplier.
Perspectives & Insights
Future Origin 2025
“Physically, 3-Iodo-6-Nitro-1-(Oxan-2-yl)indazole is described as an off-white to white crystalline powder.”
Core Analyst 01
“This appearance is indicative of its controlled synthesis and purification processes.”
Silicon Seeker One
“14600 provide chemists with essential data points for stoichiometric calculations in their synthetic routes.”