For any chemist or procurement specialist involved in the acquisition of chemical reagents, a thorough understanding of a compound's properties is fundamental. 4-Bromo-3-nitrobenzotrifluoride (CAS 349-03-1) is a specialized intermediate that offers a unique set of characteristics beneficial for advanced synthesis. This article outlines its key physical and chemical properties, providing essential information for researchers and buyers looking to source this compound effectively.

4-Bromo-3-nitrobenzotrifluoride is characterized by its distinct molecular structure. Its molecular formula is C7H3BrF3NO2, with a molecular weight of approximately 270.01 g/mol. As typically supplied by manufacturers, its appearance is described as a clear yellow liquid. This physical state is important for handling and measurement in laboratory settings.

Key physical properties, as reported by various suppliers and databases, include:

  • Boiling Point: Approximately 90 °C at 3 mmHg, indicating its volatility under reduced pressure.
  • Density: Around 1.763 g/mL at 25 °C, suggesting it is denser than water.
  • Refractive Index: Often cited around 1.511 (n20/D), which is a characteristic optical property used for identification and purity assessment.
  • Flash Point: Greater than 230 °F, indicating it is not highly flammable under standard conditions.
  • Solubility: While specific solubility data may vary, it is generally soluble in common organic solvents.

Chemically, 4-Bromo-3-nitrobenzotrifluoride is classified as an organic building block and a nitro compound. Its reactivity is defined by the functional groups present: the bromine atom is susceptible to nucleophilic substitution and palladium-catalyzed cross-coupling reactions, the nitro group can be reduced to an amino group, and the trifluoromethyl group influences the electron density of the aromatic ring and imparts lipophilicity. These reactive sites make it a versatile intermediate for preparing pharmaceuticals, agrochemicals, and other fine chemicals.

When sourcing this compound, procurement managers should look for '4-Bromo-3-nitrobenzotrifluoride 97%' or '98%' purity, as these grades are standard for most R&D applications. Understanding the 'CAS 349-03-1 price' from reputable 'chemical suppliers' in regions like China is also beneficial for budget planning. Requesting a 'free sample' and a Certificate of Analysis (CoA) from potential manufacturers is a critical step in ensuring product quality and suitability for intended synthesis pathways.

NINGBO INNO PHARMCHEM CO.,LTD. is a trusted manufacturer and supplier of 4-Bromo-3-nitrobenzotrifluoride, committed to delivering high-quality chemical intermediates. We provide detailed specifications and reliable sourcing solutions. Contact us to procure this essential compound for your next synthesis project.