Understanding the Properties of 4-Chloro-6-ethyl-5-fluoropyrimidine (CAS 137234-74-3)
4-Chloro-6-ethyl-5-fluoropyrimidine, identified by its CAS number 137234-74-3, is a specialized chemical compound that serves as a critical component in various synthetic processes, most notably in the pharmaceutical industry. Its molecular formula is C6H6ClFN2, with a molecular weight of 160.58. Typically appearing as a colorless to light yellow liquid, this compound exhibits specific physical and chemical properties that make it suitable for complex organic synthesis. Understanding these characteristics is essential for optimizing its use in drug manufacturing and research.
The primary application of 4-Chloro-6-ethyl-5-fluoropyrimidine lies in its role as an intermediate for Voriconazole, a powerful antifungal medication. Voriconazole is widely used to treat severe, invasive fungal infections that are often life-threatening, particularly in patients with weakened immune systems. The precise molecular structure of 4-Chloro-6-ethyl-5-fluoropyrimidine provides the necessary chemical framework upon which the final Voriconazole molecule is built, highlighting its importance as a pharmaceutical intermediate.
Key properties such as its boiling point (211°C), density (1.286), flash point (81°C), and refractive index (1.496) are crucial data points for chemists and process engineers. These parameters inform handling, storage, and reaction conditions, ensuring safe and efficient utilization. For instance, its flash point indicates the temperature at which it can vaporize to form an ignitable mixture in air, guiding safety protocols in manufacturing environments.
As a chemical building block, 4-Chloro-6-ethyl-5-fluoropyrimidine facilitates the introduction of specific functional groups into target molecules. Its fluorinated pyrimidine structure is particularly valuable in medicinal chemistry for its influence on a drug's pharmacokinetic properties, such as metabolic stability and bioavailability. This makes it an attractive compound for drug discovery and development pipelines.
NINGBO INNO PHARMCHEM CO.,LTD. is a dedicated pharmaceutical intermediates supplier, committed to delivering high-quality 4-Chloro-6-ethyl-5-fluoropyrimidine to meet the demanding needs of the pharmaceutical sector. Our focus on providing reliable Voriconazole synthesis intermediates ensures that our clients can proceed with their research and production with confidence. The consistent availability and purity of this compound are vital for the uninterrupted supply of essential antifungal therapies. By understanding the intricate CAS 137234-74-3 chemical properties, we empower our clients to achieve their synthesis goals effectively.
The primary application of 4-Chloro-6-ethyl-5-fluoropyrimidine lies in its role as an intermediate for Voriconazole, a powerful antifungal medication. Voriconazole is widely used to treat severe, invasive fungal infections that are often life-threatening, particularly in patients with weakened immune systems. The precise molecular structure of 4-Chloro-6-ethyl-5-fluoropyrimidine provides the necessary chemical framework upon which the final Voriconazole molecule is built, highlighting its importance as a pharmaceutical intermediate.
Key properties such as its boiling point (211°C), density (1.286), flash point (81°C), and refractive index (1.496) are crucial data points for chemists and process engineers. These parameters inform handling, storage, and reaction conditions, ensuring safe and efficient utilization. For instance, its flash point indicates the temperature at which it can vaporize to form an ignitable mixture in air, guiding safety protocols in manufacturing environments.
As a chemical building block, 4-Chloro-6-ethyl-5-fluoropyrimidine facilitates the introduction of specific functional groups into target molecules. Its fluorinated pyrimidine structure is particularly valuable in medicinal chemistry for its influence on a drug's pharmacokinetic properties, such as metabolic stability and bioavailability. This makes it an attractive compound for drug discovery and development pipelines.
NINGBO INNO PHARMCHEM CO.,LTD. is a dedicated pharmaceutical intermediates supplier, committed to delivering high-quality 4-Chloro-6-ethyl-5-fluoropyrimidine to meet the demanding needs of the pharmaceutical sector. Our focus on providing reliable Voriconazole synthesis intermediates ensures that our clients can proceed with their research and production with confidence. The consistent availability and purity of this compound are vital for the uninterrupted supply of essential antifungal therapies. By understanding the intricate CAS 137234-74-3 chemical properties, we empower our clients to achieve their synthesis goals effectively.
Perspectives & Insights
Future Origin 2025
“Its fluorinated pyrimidine structure is particularly valuable in medicinal chemistry for its influence on a drug's pharmacokinetic properties, such as metabolic stability and bioavailability.”
Core Analyst 01
“This makes it an attractive compound for drug discovery and development pipelines.”
Silicon Seeker One
“is a dedicated pharmaceutical intermediates supplier, committed to delivering high-quality 4-Chloro-6-ethyl-5-fluoropyrimidine to meet the demanding needs of the pharmaceutical sector.”