4-Iodoaniline (CAS 540-37-4) is a chemical compound that holds significant value due to its distinct reactivity, making it a sought-after intermediate in various industrial and research applications. Understanding its chemical characteristics is key for chemists and procurement specialists looking to leverage its potential. NINGBO INNO PHARMCHEM CO.,LTD., a leading manufacturer and supplier, offers high-quality 4-iodoaniline to meet these demands.

The chemical structure of 4-Iodoaniline is central to its utility. As an aniline derivative, it possesses an amino group (-NH2) which can undergo reactions typical of primary amines, such as acylation and alkylation. More importantly, the iodine atom attached to the aromatic ring is a good leaving group, facilitating a wide array of cross-coupling reactions. These include:

Palladium-Catalyzed Cross-Coupling Reactions:

  • Suzuki Coupling: Reaction with boronic acids to form new carbon-carbon bonds, crucial for constructing complex aromatic systems.
  • Heck Reaction: Coupling with alkenes to introduce vinyl groups onto the aromatic ring.
  • Sonogashira Coupling: Reaction with terminal alkynes to create carbon-carbon triple bonds, essential for synthesizing conjugated systems.
  • Buchwald-Hartwig Amination: Formation of carbon-nitrogen bonds by coupling with amines.

These reactions enable chemists to efficiently synthesize a wide range of complex organic molecules. When you buy 4-iodoaniline, you are investing in a versatile tool for molecular construction.

The applications stemming from this reactivity are diverse. In the pharmaceutical industry, 4-iodoaniline is a key intermediate for synthesizing drug candidates targeting various diseases. Its role in creating specific molecular architectures is vital for developing APIs with desired pharmacological profiles. NINGBO INNO PHARMCHEM, as a supplier of pharmaceutical-grade intermediates, ensures the purity required for these sensitive applications.

In the dye and pigment industry, 4-iodoaniline serves as a precursor for producing vibrant and stable colorants. The iodine substitution can influence the electronic properties of the resulting dyes, leading to specific shades and improved performance characteristics like lightfastness.

For researchers and industrial chemists looking to purchase CAS 540-37-4, choosing a reliable manufacturer like NINGBO INNO PHARMCHEM is essential. We provide 4-iodoaniline with a minimum purity of 99.0%, supported by comprehensive technical data. Whether you are developing new pharmaceuticals or advanced materials, our commitment to quality and consistent supply ensures you have the chemical building blocks you need. Inquire today for pricing and availability.