For professionals in the pharmaceutical and fine chemical industries, understanding the precise specifications of chemical intermediates is fundamental to successful research, development, and manufacturing. 5,6-Diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride, identified by CAS number 312753-53-0, is a key intermediate, notably for the synthesis of Indacaterol. This article provides a comprehensive overview of its critical specifications, offering valuable insights for R&D scientists and procurement managers who need to buy or inquire about this compound.

The most immediately observable specification is the appearance. 5,6-Diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride is typically described as a white to off-white powder. This physical characteristic is a primary indicator of product quality and consistency. Any significant deviation from this description might suggest contamination or degradation, necessitating further investigation before use.

The assay, or purity, is arguably the most critical specification for any pharmaceutical intermediate. For 5,6-Diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride, a common and acceptable standard is ≥98.0%. This means that at least 98.0% of the material consists of the desired compound, with the remaining percentage comprising impurities. High assay values are vital to ensure the efficiency of subsequent synthetic steps and the purity of the final API. Manufacturers achieve this through optimized synthesis and rigorous purification processes.

The molecular formula (C13H20ClN) and molecular weight (225.758 g/mol) are fundamental chemical identifiers. These properties are crucial for stoichiometric calculations in synthetic reactions and for analytical method development. Understanding these values helps scientists predict the behavior of the compound in various chemical processes.

Packaging specifications are also important for practical handling and storage. Typically, this intermediate is supplied in 25 kg drums. However, reputable suppliers also offer flexibility to package according to customer requirements, which is invaluable for both small-scale R&D projects and larger manufacturing campaigns. Ensuring appropriate packaging protects the compound from moisture, light, and contamination.

Storage conditions are critical for maintaining the integrity and shelf-life of the chemical. The compound should be stored in a cool, well-ventilated place. Adhering to recommended storage conditions prevents degradation and ensures the product remains within its specified purity limits until it is used.

The primary application as an intermediate in the synthesis of Indacaterol highlights its significance in the pharmaceutical industry. This role means that demand for this intermediate is directly tied to the market for Indacaterol-based COPD treatments. Researchers developing new synthetic routes or exploring variations of Indacaterol would also require this compound.

For procurement professionals looking to purchase 5,6-Diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride, understanding these specifications allows for informed decision-making. It enables effective comparison of offers from different manufacturers and ensures that the procured material aligns with the stringent requirements of pharmaceutical development. Partnering with manufacturers like NINGBO INNO PHARMCHEM CO., LTD., who clearly define and consistently meet these specifications, is key to a successful and reliable supply chain for this vital pharmaceutical intermediate.