The intricate world of organic synthesis often hinges on the availability and quality of key intermediate compounds. Tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate, identified by CAS number 571188-59-5, is one such compound that plays a pivotal role in modern pharmaceutical research and manufacturing. Its primary application as an intermediate in the synthesis of Palbociclib, a drug revolutionizing breast cancer treatment, highlights its significance.

The synthesis of tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate typically involves reduction reactions. A common method includes the hydrogenation of its nitro precursor, tert-butyl 4-(6-nitropyridin-3-yl)piperazine-1-carboxylate, often using a palladium-on-carbon catalyst under a hydrogen atmosphere. This process yields the desired amino compound with high efficiency, often exceeding 97% yield. NINGBO INNO PHARMCHEM CO.,LTD. employs optimized synthesis routes to ensure the consistent production of this vital pharmaceutical intermediate, adhering to strict purity standards of ≥98.5%.

Beyond its direct use in Palbociclib synthesis, tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate is a versatile molecule for various organic chemistry applications. Its bifunctional nature – possessing both a protected amine and a reactive primary amine – allows for diverse derivatization and coupling reactions. Researchers and manufacturers looking to buy this compound can leverage its structure for developing new chemical entities, exploring novel drug discovery pathways, or creating advanced materials. The ability to purchase this intermediate at a competitive price from a reputable supplier like NINGBO INNO PHARMCHEM CO.,LTD. is crucial for these endeavors.

The chemical properties, such as its molecular weight of 278.35 g/mol and specific physical characteristics (e.g., appearance as a white to brown powder), are well-documented and critical for chemists to consider during reaction planning. NINGBO INNO PHARMCHEM CO.,LTD. provides comprehensive product information, ensuring that our clients have all the necessary data to integrate this intermediate seamlessly into their synthesis protocols. As a leading manufacturer in China, we are dedicated to advancing chemical synthesis through the provision of high-quality intermediates.