In the realm of fine chemicals and specialized intermediates, 5-Bromo-2,4-difluoroaniline (CAS 452-92-6) is a compound of significant interest. This halogenated aniline derivative, appearing as a white crystalline powder, serves as a critical building block in various advanced chemical syntheses, particularly within the pharmaceutical and agrochemical sectors. As a manufacturer and supplier committed to quality, we aim to provide comprehensive information about this versatile intermediate, empowering our clients to make informed purchasing decisions.

The molecular structure of 5-Bromo-2,4-difluoroaniline, C6H4BrF2N, is characterized by an aniline core with a bromine atom at the 5-position and fluorine atoms at the 2- and 4-positions. This unique arrangement of electron-withdrawing groups imbues the molecule with distinct reactivity, making it highly suitable for a range of chemical transformations. Typically supplied with a purity of 98% or higher, it is crucial for applications demanding precision and reliability.

The synthesis of 5-Bromo-2,4-difluoroaniline can be achieved through several established methods. One common approach involves the direct bromination of 2,4-difluoroaniline using bromine or suitable brominating agents. Other routes might involve nucleophilic substitution reactions on pre-functionalized aromatic systems. For researchers and manufacturers looking to buy 5-Bromo-2,4-difluoroaniline, understanding these synthesis pathways can be beneficial for quality assessment and supplier evaluation. Leading Chinese manufacturers often employ optimized processes to ensure high yields and purity.

The applications of 5-Bromo-2,4-difluoroaniline are diverse and impactful. In medicinal chemistry, it acts as a key intermediate for synthesizing complex drug molecules, including anticancer agents like lapatinib, antipsychotics such as cariprazine, and antiviral compounds. Its utility extends to the agrochemical industry for developing advanced pesticides. Furthermore, its reactive sites make it valuable in material science and as a precursor for specialty organic chemicals. When seeking to procure this intermediate, a focus on purity and consistent supply from reputable Chinese manufacturers is advisable.

For those in the chemical research and manufacturing industries, understanding the properties and sourcing of critical intermediates like 5-Bromo-2,4-difluoroaniline is key to success. By partnering with experienced Chinese suppliers, you can ensure access to high-quality materials that meet stringent requirements, facilitating the development of groundbreaking products.