For chemists and researchers working with heterocyclic compounds, a thorough understanding of the properties and synthesis of key intermediates like 3,5-Dichloropyridazine (CAS: 1837-55-4) is crucial. NINGBO INNO PHARMCHEM CO.,LTD. provides this vital chemical, along with insights into its handling and preparation, to facilitate seamless research and development.

3,5-Dichloropyridazine presents itself as a yellow to dark orange solid, with a melting point typically ranging from 60.0 to 64.0 °C. Its molecular formula is C4H2Cl2N2, and it possesses a molecular weight of approximately 148.98 g/cm³. These physical characteristics, along with its stability under normal storage conditions (kept in dark, sealed, dry, at room temperature), make it manageable for laboratory and industrial use. The compound's predicted pKa of -0.25±0.10 suggests its acidic nature.

The preparation of 3,5-Dichloropyridazine often involves a multi-step process. A common method includes reacting 2,4,4,4-Tetrachlorocrotonaldehyde with a mixture of semicarbazide hydrochloride, water, and a solvent under controlled temperatures. Following the reaction, solvent removal and precipitation through cooling, often followed by recrystallization using solvent mixtures like dichloromethane/petroleum ether, yields the desired compound as a solid.

The high purity of 3,5-Dichloropyridazine, often exceeding 97%, is critical for its application as a pharmaceutical and agrochemical intermediate. Impurities can significantly affect the yield and purity of the final product, compromising its efficacy. NINGBO INNO PHARMCHEM CO.,LTD. ensures that its supply of 3,5-Dichloropyridazine meets these stringent quality demands, supporting the reliable synthesis of complex molecules.