Understanding Thioflavin T: Chemical Properties and Research Applications
Thioflavin T (CAS 2390-54-7) is a specialized chemical compound widely utilized in scientific research, particularly in the fields of biochemistry and cell biology. As a leading provider of fine chemicals, we understand the importance of detailed information for researchers to make informed decisions. This article outlines the fundamental chemical properties of Thioflavin T and its diverse research applications, highlighting why it's a must-have reagent for many laboratories. If you're looking to buy Thioflavin T, understanding its characteristics is the first step.
Thioflavin T is a cationic benzothiazole dye recognized for its distinctive fluorescence properties. Its primary application lies in detecting and quantifying amyloid fibrils, which are protein aggregates associated with various neurodegenerative diseases, including Alzheimer's disease. When Thioflavin T binds to the beta-sheet rich structures of amyloid fibrils, it exhibits a significant increase in fluorescence intensity. This allows researchers to visualize and measure the extent of protein aggregation in both in vitro experimental settings and in biological tissue samples. The reliability of this assay is directly linked to the purity of the Thioflavin T used, making it crucial to source from a reputable Thioflavin T supplier.
Chemically, Thioflavin T has the molecular formula C17H19ClN2S and a molecular weight of 318.86 g/mol. It typically presents as a yellow to ochre-yellow powder and exhibits good solubility in methanol and DMSO, which are common solvents in biological research. Proper storage conditions, usually at room temperature or refrigerated and protected from light, are essential for maintaining its stability and efficacy. As a dedicated Thioflavin T manufacturer in China, we ensure that our product meets stringent purity standards, typically exceeding 97% by HPLC.
In addition to its role in amyloid research, Thioflavin T is also employed in histology for staining neuronal cell bodies and nucleoli, offering a fluorescent alternative to traditional stains. This application is particularly valuable in neuroscience research for visualizing neural tissue architecture. The dye's versatility means it's a key component in studies investigating protein dynamics, cellular stress, and even as a probe in certain diagnostic assays. Researchers often seek to understand the Thioflavin T price in relation to its performance and reliability.
Procuring Thioflavin T from a dependable source is crucial for the consistency and validity of your research data. Our commitment as a Thioflavin T supplier ensures that you receive a high-quality product, backed by comprehensive technical documentation. We facilitate the process for you to purchase Thioflavin T, ensuring timely delivery and responsive customer support. Whether for fundamental research, drug screening, or diagnostic development, Thioflavin T remains an indispensable chemical tool.
Perspectives & Insights
Logic Thinker AI
“As a dedicated Thioflavin T manufacturer in China, we ensure that our product meets stringent purity standards, typically exceeding 97% by HPLC.”
Molecule Spark 2025
“In addition to its role in amyloid research, Thioflavin T is also employed in histology for staining neuronal cell bodies and nucleoli, offering a fluorescent alternative to traditional stains.”
Alpha Pioneer 01
“This application is particularly valuable in neuroscience research for visualizing neural tissue architecture.”