Understanding Thymidine (CAS 50-89-5): A Comprehensive Guide for Researchers
Thymidine, with its CAS number 50-89-5, is a critical deoxynucleoside that forms a fundamental part of the DNA molecule. Its chemical structure, a pyrimidine base (thymine) linked to a deoxyribose sugar, dictates its unique role in biological systems. For researchers in molecular biology, genetics, and pharmaceutical sciences, a thorough understanding of Thymidine’s properties and applications is essential for successful experimentation.
Chemically, Thymidine is a white crystalline powder with specific solubility characteristics, typically soluble in water and various organic solvents. Its melting point is around 186-188°C. These properties are important considerations for its handling and use in laboratory settings. The primary biological function of Thymidine is its specific pairing with adenine in DNA, a critical step in DNA replication and genetic information storage. It also serves as a precursor for thymidine triphosphate (dTTP), the activated form required for DNA chain elongation.
In experimental settings, Thymidine is widely recognized for its utility in cell cycle studies. By adding Thymidine to cell cultures, researchers can induce cell cycle arrest at the G1/S boundary, a phenomenon known as 'thymidine block.' This allows for the synchronization of cell populations, which is invaluable for studying DNA synthesis kinetics, cell division processes, and the impact of various treatments on these events. Consequently, obtaining Thymidine from a reliable supplier, especially those offering it from China, ensures the purity and consistency needed for these precise applications.
Whether investigating DNA synthesis rates, exploring mechanisms of DNA repair, or developing new therapeutic agents that target DNA replication, Thymidine is an indispensable biochemical reagent. Its consistent and reliable supply is crucial for the advancement of scientific knowledge in these vital areas.
Chemically, Thymidine is a white crystalline powder with specific solubility characteristics, typically soluble in water and various organic solvents. Its melting point is around 186-188°C. These properties are important considerations for its handling and use in laboratory settings. The primary biological function of Thymidine is its specific pairing with adenine in DNA, a critical step in DNA replication and genetic information storage. It also serves as a precursor for thymidine triphosphate (dTTP), the activated form required for DNA chain elongation.
In experimental settings, Thymidine is widely recognized for its utility in cell cycle studies. By adding Thymidine to cell cultures, researchers can induce cell cycle arrest at the G1/S boundary, a phenomenon known as 'thymidine block.' This allows for the synchronization of cell populations, which is invaluable for studying DNA synthesis kinetics, cell division processes, and the impact of various treatments on these events. Consequently, obtaining Thymidine from a reliable supplier, especially those offering it from China, ensures the purity and consistency needed for these precise applications.
Whether investigating DNA synthesis rates, exploring mechanisms of DNA repair, or developing new therapeutic agents that target DNA replication, Thymidine is an indispensable biochemical reagent. Its consistent and reliable supply is crucial for the advancement of scientific knowledge in these vital areas.
Perspectives & Insights
Nano Explorer 01
“Chemically, Thymidine is a white crystalline powder with specific solubility characteristics, typically soluble in water and various organic solvents.”
Data Catalyst One
“These properties are important considerations for its handling and use in laboratory settings.”
Chem Thinker Labs
“The primary biological function of Thymidine is its specific pairing with adenine in DNA, a critical step in DNA replication and genetic information storage.”