Trometamol, commonly known as Tris buffer, bearing the CAS number 77-86-1, is a chemical compound that holds significant importance across various scientific and industrial disciplines. Presented typically as a white crystalline powder, its consistent chemical properties and broad applicability make it a sought-after material for buyers focused on precision and reliability. Understanding its chemical profile and sourcing options is crucial for researchers, formulators, and procurement specialists alike.

Chemically, Trometamol is a primary amine with three hydroxyl groups, giving it the formula C4H11NO3. This structure dictates its behavior as an effective buffering agent. Its pKa value, approximately 8.07 at 25°C, positions it ideally for maintaining stable pH in biological systems, generally between pH 7.0 and 9.0. This range encompasses the physiological pH of many organisms, making it a staple in biochemical research, particularly in preparing buffer solutions for techniques like gel electrophoresis (e.g., TAE and TBE buffers) and for protein purification. The need for high-purity Trometamol (often >99%) in these applications underscores the importance of selecting a reputable supplier.

The utility of Trometamol extends significantly into the pharmaceutical sector. It serves as a key pharmaceutical intermediate, facilitating the synthesis of various medicinal compounds. Moreover, its role as an excipient in pharmaceutical products, including vaccines, is a growing area of application. In vaccine formulations, it helps stabilize delicate biomolecules, ensuring product efficacy and shelf life. Companies in the pharmaceutical industry looking to buy Trometamol prioritize consistent quality and adherence to regulatory standards, often seeking detailed analytical data from their manufacturers. Competitive pricing for this essential chemical is a major consideration for bulk orders.

In industrial contexts, Trometamol contributes to the formulation of coatings, where it can function as a dispersant and a formaldehyde scavenger. This dual action can improve coating performance and meet environmental requirements. Additionally, it finds application as a surfactant precursor and as a curing accelerator in various chemical processes, contributing to material properties. Procurement professionals in these industries often seek cost-effective solutions, making the search for reliable Tris buffer suppliers, particularly those offering competitive rates from regions like China, a strategic priority.

Key considerations when sourcing Trometamol include not only its purity and physical form but also understanding its properties like solubility and its sensitivity to temperature changes, which can affect its buffering capacity. For B2B buyers, identifying a dependable manufacturer that can provide consistent quality, timely delivery, and favorable pricing is paramount. We are a dedicated provider of Trometamol (CAS 77-86-1), offering high-purity grades suitable for a wide range of applications. We invite you to contact us to discuss your specific needs, obtain a quotation, and explore how we can be your trusted partner for this essential chemical.