In the realm of biochemistry and metabolic research, understanding the complex pathways of essential amino acids is crucial. Tryptophan (TRP), an essential amino acid, is a precursor to various bioactive compounds, including serotonin and kynurenine metabolites. Among these, 5-Hydroxyanthranilic Acid (CAS 394-31-0) is a notable metabolite with growing research interest, particularly concerning its role in metabolic health and its potential association with conditions like Type 2 Diabetes Mellitus (T2DM).

5-Hydroxyanthranilic Acid as a Tryptophan Metabolite

Research indicates that imbalances in tryptophan metabolism, specifically elevated levels of certain metabolites like 5-Hydroxyanthranilic Acid, may be linked to metabolic disorders. Studies have observed higher plasma levels of this compound in patients with T2DM compared to healthy individuals. While its precise mechanism in these conditions is still under investigation, its presence in these pathways highlights its importance in biological processes. For researchers studying these metabolic pathways, obtaining a pure and reliable source of 5-Hydroxyanthranilic Acid is essential for accurate experimental outcomes. As a fine chemical intermediate, it is available from various suppliers.

Procurement for Research and Development

For R&D scientists and procurement specialists looking to buy 5-Hydroxyanthranilic Acid for biochemical research, the following points are vital:

  • Purity for Research: High purity (e.g., >98%) is critical for biochemical assays to ensure accurate results and avoid confounding factors from impurities. Verify the product specifications from the manufacturer.
  • Supplier Reputation: Choose a supplier with a good reputation in the research chemical market, known for quality and reliable delivery. Many leading manufacturers in China are a good starting point.
  • Quantity Requirements: Research quantities often range from grams to kilograms. Understand the available packaging and minimum order quantities to align with your project needs.
  • Cost-Effectiveness: While quality is paramount, comparing prices from different suppliers is prudent. Look for competitive pricing without compromising on purity.
  • Documentation: Requesting a Certificate of Analysis (CoA) and potentially a Material Safety Data Sheet (MSDS) is standard for laboratory use.

Accessing 5-Hydroxyanthranilic Acid

Accessing high-quality 5-Hydroxyanthranilic Acid for your research endeavors is straightforward. Numerous chemical suppliers and direct manufacturers offer this compound. By leveraging online platforms and industry networks, you can connect with reliable providers, obtain quotes, and ensure a steady supply for your studies on tryptophan metabolism or other related research areas. Partnering with established suppliers in China can offer a cost-effective solution for acquiring this important biochemical intermediate.