NINGBO INNO PHARMCHEM CO.,LTD. is at the forefront of supplying essential chemical building blocks that fuel scientific discovery and industrial innovation. Among these, Z-amino acids, characterized by the carbobenzyloxy (Z) protecting group, play a vital role. This article focuses on Z-Glu-OH (CAS: 1155-62-0), highlighting its significance in research and development.

The Z-group is a classic and highly effective protecting group for the amine functionality of amino acids. Its introduction, typically via reaction with benzyl chloroformate, allows for selective manipulation of other functional groups within a molecule. For Z-Glu-OH, this means the alpha-amino group of glutamic acid is shielded, enabling chemists to perform reactions on the side-chain carboxyl group or the alpha-carboxyl group without interference. This selective protection is fundamental to achieving controlled synthesis of peptides and other complex organic molecules. Researchers often buy Z-Glu-OH when they need a reliable source of protected glutamic acid for peptide synthesis or for building chiral intermediates.

The stability and removal conditions of the Z group are critical to its utility. Typically removed by catalytic hydrogenation (e.g., using palladium on carbon), this method is orthogonal to many other protecting groups, allowing for complex synthetic strategies. This characteristic makes Z-Glu-OH a preferred choice in multi-step synthesis where preserving specific functionalities is paramount. The price of Z-Glu-OH often reflects the rigor of its synthesis and purification, ensuring it meets the high standards required for scientific research. Understanding the sourcing and price of Z-Glu-OH is crucial for R&D planning.

The applications of Z-Glu-OH span various scientific disciplines. In academic laboratories and industrial R&D departments, it serves as a versatile intermediate for synthesizing peptides with specific sequences, developing novel pharmaceuticals, and exploring new materials. Its role as a key component in creating peptide libraries for drug screening further emphasizes its importance. NINGBO INNO PHARMCHEM CO.,LTD. is proud to support these endeavors by providing high-quality Z-amino acid for peptide synthesis, contributing to the progress of scientific understanding and the development of new products.