For organic chemists engaged in complex synthesis projects, the selection of reliable and high-quality building blocks is paramount. Z-Met-OH, or N-Cbz-L-methionine (CAS 1152-62-1), is one such critical intermediate, valued for its protected amino acid structure and the versatile reactivity it offers. Understanding its chemical properties and applications can significantly enhance the efficiency and success of various synthetic routes, from pharmaceuticals to novel materials.

Chemical Profile of Z-Met-OH

Z-Met-OH is a derivative of the naturally occurring amino acid methionine. It features a Cbz (Benzyloxycarbonyl) protecting group on the alpha-amino nitrogen and the free carboxylic acid at the other end. Its key characteristics include:

  • Chemical Name: N-Cbz-L-methionine or N-Benzyloxycarbonyl-L-methionine
  • CAS Number: 1152-62-1
  • Molecular Formula: C13H17NO4S
  • Molecular Weight: 283.34 g/mol
  • Appearance: Typically a white to off-white powder.

The presence of the Cbz group makes Z-Met-OH suitable for stepwise peptide synthesis, as well as for modifications or coupling reactions where the amino group needs to be temporarily deactivated. The methionine moiety, with its thioether side chain, can also participate in various sulfur-based chemical transformations.

Applications in Organic Synthesis

Z-Met-OH is a versatile intermediate used in:

  • Peptide Synthesis: As a protected amino acid, it is a fundamental building block for creating peptides, crucial in medicinal chemistry and biochemistry.
  • Synthesis of Modified Amino Acids: It can serve as a starting point for synthesizing various modified methionine derivatives.
  • Drug Intermediates: Its structure can be incorporated into larger, complex molecules that serve as active pharmaceutical ingredients (APIs) or key intermediates in API synthesis.
  • Biochemical Research: Used in studies related to enzyme inhibition, protein structure, and metabolic pathways where methionine or its derivatives are involved.

Importance of Sourcing from a Reputable Z-Met-OH Manufacturer

For any synthetic chemist, the quality and consistency of starting materials are non-negotiable. Sourcing Z-Met-OH from a trusted manufacturer ensures that you receive a product with confirmed purity, reliable specifications, and consistent batch-to-batch performance. Working with a reputable Z-Met-OH supplier, such as NINGBO INNO PHARMCHEM CO.,LTD., guarantees that you obtain materials suitable for demanding synthetic routes, minimizing the risk of failed reactions or laborious purification processes. We offer high-purity Z-Met-OH, backed by rigorous quality control and technical support, to meet your diverse organic synthesis needs. Explore our offerings and contact us to buy Z-Met-OH for your next project.