Unlock Peptide Synthesis: The Role of H-Glu(OtBu)-OH
In the intricate world of peptide synthesis, the selection of high-quality building blocks is paramount. Among these, protected amino acid derivatives play a critical role in ensuring the success and purity of the final peptide product. One such vital compound is H-Glu(OtBu)-OH, also known as L-Glutamic acid gamma-tert-butyl ester. Understanding its properties and applications is essential for any researcher or chemist involved in peptide-related projects.
H-Glu(OtBu)-OH is an essential amino acid derivative widely utilized in both solid-phase and solution-phase peptide synthesis. Its primary function stems from the tert-butyl ester protecting group on the gamma-carboxyl function of glutamic acid. This protection strategy is crucial as it prevents unwanted side reactions during peptide chain elongation, allowing for precise control over the coupling process. The 'H-' prefix indicates that the amino group is free, ready for reaction with the activated carboxyl group of the next amino acid or peptide chain.
For researchers looking to buy H-Glu(OtBu)-OH, ensuring high purity is key. The CAS number for this compound is 2419-56-9. Its molecular formula is C9H17NO4, with a molecular weight of approximately 203.2 g/mol. Typically supplied as a solid, its melting point and optical rotation are important quality indicators. As a leading manufacturer in China, we are committed to providing H-Glu(OtBu)-OH that meets stringent quality standards, making it a reliable choice for your custom peptide synthesis needs.
The strategic use of H-Glu(OtBu)-OH in peptide synthesis contributes significantly to achieving cleaner reaction profiles and higher yields of target peptides. This makes it an invaluable tool when exploring the amino acid derivatives for peptide synthesis. Whether you are working on synthesizing therapeutic peptides, research probes, or complex peptidomimetics, the consistent quality of your starting materials directly impacts your outcomes. This derivative is also fundamental for those researching L-Glutamic acid gamma-tert-butyl ester properties, offering a well-defined building block for various chemical transformations.
When considering the H-Glu(OtBu)-OH synthesis, it's important to work with suppliers who adhere to rigorous manufacturing practices. We pride ourselves on being a dependable supplier, offering this critical reagent for your scientific endeavors. By utilizing H-Glu(OtBu)-OH, you can streamline your synthesis processes and focus on the broader goals of your research, confident in the quality of the materials you are using. Explore the benefits of incorporating this high-quality amino acid derivative into your peptide synthesis workflow.
Perspectives & Insights
Agile Reader One
“Its primary function stems from the tert-butyl ester protecting group on the gamma-carboxyl function of glutamic acid.”
Logic Vision Labs
“This protection strategy is crucial as it prevents unwanted side reactions during peptide chain elongation, allowing for precise control over the coupling process.”
Molecule Origin 88
“The 'H-' prefix indicates that the amino group is free, ready for reaction with the activated carboxyl group of the next amino acid or peptide chain.”