The relentless pursuit of new chemical entities and advanced materials drives innovation across the pharmaceutical, agrochemical, and materials science sectors. At the heart of this endeavor lies the strategic use of specialized chemical intermediates. 4-Bromo-2,3,5,6-tetrafluoropyridine (CAS 3511-90-8) is one such compound, offering a unique set of chemical properties that make it indispensable for researchers aiming to push the boundaries of chemical synthesis.

The Power of Fluorination and Halogenation

What makes 4-Bromo-2,3,5,6-tetrafluoropyridine so valuable? It’s the synergistic combination of a halogen atom (bromine) and multiple fluorine atoms on a pyridine ring. The bromine atom acts as a versatile leaving group or a point of attachment for cross-coupling reactions, such as the widely used Suzuki-Miyaura coupling. The fluorine atoms, with their high electronegativity, significantly alter the electronic landscape of the pyridine ring, influencing its reactivity and the properties of molecules derived from it. This makes it an excellent precursor for synthesizing novel compounds with enhanced characteristics, like increased stability, altered lipophilicity, and modified biological activity. Its typical purity of 97% ensures reliable performance in demanding research applications.

Key Applications in Chemical Research

Researchers utilize 4-Bromo-2,3,5,6-tetrafluoropyridine in a variety of critical applications. It serves as a fundamental building block in the synthesis of complex organic molecules. Its ability to form organometallic reagents, such as tetrafluoro-pyridylcadmium and tetrafluoro-pyridylzinc, is particularly noteworthy. These reagents are instrumental in modern organic synthesis for forming new carbon-carbon bonds, a foundational step in creating drug candidates, pesticides, and functional materials. Scientists developing new catalysts, electronic materials, or pharmaceutical ingredients often find this fluorinated pyridine derivative to be a vital component in their synthetic routes. The compound's liquid form and manageable boiling point further facilitate its use in standard laboratory setups.

Strategic Sourcing: Finding Quality and Value

For R&D departments and chemical purchasers worldwide, sourcing high-quality intermediates at a competitive price is a constant objective. China has established itself as a leading hub for the manufacturing of fine chemicals, offering a robust supply chain for compounds like 4-Bromo-2,3,5,6-tetrafluoropyridine. When you aim to buy this crucial intermediate, partnering with Chinese manufacturers can provide significant advantages. These suppliers often offer direct-from-manufacturer pricing, which is typically more favorable than through intermediaries. Furthermore, many Chinese chemical companies are equipped with advanced synthesis capabilities and adhere to strict quality control standards, ensuring you receive a product that meets your purity requirements. When evaluating potential suppliers, consider their experience, product specifications, and responsiveness to inquiries.

The Path to Procurement Success

Securing a reliable supply of 4-Bromo-2,3,5,6-tetrafluoropyridine is crucial for uninterrupted research. As you navigate the procurement process, focus on suppliers who offer transparent pricing, detailed product information (like CAS numbers and purity levels), and efficient customer service. Many reputable manufacturers will provide a quote upon request and may offer free samples for initial evaluation. By strategically choosing your supplier, you can ensure that you not only acquire the necessary chemical intermediate but also optimize your R&D budget and timelines. The value this compound brings to chemical innovation makes its efficient procurement a worthwhile endeavor.

In conclusion, 4-Bromo-2,3,5,6-tetrafluoropyridine is a pivotal intermediate for unlocking new possibilities in chemical research and development. Its unique fluorinated structure and reactivity, combined with strategic sourcing from reliable manufacturers, empower scientists to drive groundbreaking discoveries.