The field of organic synthesis is continuously evolving, driven by the demand for novel molecules with diverse applications, particularly in pharmaceuticals and materials science. Among the vast array of chemical building blocks, heterocyclic compounds with halogen substituents play a pivotal role. This article highlights the versatility of brominated quinazolines, focusing on the utility and sourcing of 7-Bromo-4-chloro-2-methylquinazoline (CAS: 403850-84-0).

The Chemical Profile of Brominated Quinazolines

Quinazolines are bicyclic aromatic heterocycles containing a benzene ring fused to a pyrimidine ring. The introduction of a bromine atom onto this scaffold, as seen in 7-Bromo-4-chloro-2-methylquinazoline, significantly enhances its synthetic utility. The carbon-bromine bond is highly susceptible to various palladium-catalyzed cross-coupling reactions, such as Suzuki, Stille, and Heck couplings. These reactions allow chemists to introduce a wide range of functional groups and create more complex molecular structures.

The presence of a chlorine atom and a methyl group further increases the reactivity and selectivity options for chemists working with 7-Bromo-4-chloro-2-methylquinazoline. This trifunctionalized molecule acts as a versatile platform for constructing complex chemical entities, making it highly sought after by researchers and manufacturers.

Applications and Research Opportunities

7-Bromo-4-chloro-2-methylquinazoline (CAS: 403850-84-0) finds its primary applications as a critical intermediate in:

  • Pharmaceutical Research: Many drug candidates incorporate quinazoline motifs for their biological activity. The bromine atom provides a handle for diversification, enabling the rapid synthesis of libraries of compounds for screening.
  • Agrochemical Development: Similar to pharmaceuticals, the quinazoline structure can impart desirable properties in pesticides and herbicides.
  • Materials Science: The electronic properties of halogenated heterocycles are of interest for developing new electronic materials and organic semiconductors.

Researchers looking to buy this compound for their innovative projects can benefit from a reliable supplier who ensures high purity and consistent quality.

Sourcing High-Quality Intermediates

When procuring chemical intermediates like 7-Bromo-4-chloro-2-methylquinazoline, partnering with a reputable manufacturer is crucial. We are a leading supplier from China, dedicated to providing intermediates with a guaranteed minimum purity of 97%. Our commitment to quality ensures that your synthetic reactions proceed smoothly and efficiently. We provide comprehensive technical documentation and are always available to discuss your specific needs and provide pricing and sample information.

To unlock the synthetic potential of brominated quinazolines, rely on a trusted source. Contact us for your requirements of 7-Bromo-4-chloro-2-methylquinazoline (CAS: 403850-84-0) and let us be your partner in chemical innovation.