In the relentless pursuit of more effective cancer treatments, biochemical research plays a pivotal role. Among the many critical compounds used in these investigations, 2'-Deoxyuridine 5'-monophosphate disodium salt stands out due to its specific applications in understanding and developing chemotherapy agents. This article delves into the significance of this compound and how researchers can leverage its properties to advance their work.

The primary utility of 2'-Deoxyuridine 5'-monophosphate disodium salt lies in its function as a reference substrate for the enzyme thymidylate synthetase (TS) (EC 2.1.1.45). This enzyme is fundamental in the de novo production of deoxythymidine monophosphate (dTMP), a crucial building block for DNA synthesis. By providing a reliable source of dUMP, researchers can accurately study the activity and inhibition of TS, a common target in cancer chemotherapy.

Furthermore, 2'-Deoxyuridine 5'-monophosphate disodium salt is invaluable in the study of dUMP analogues. These analogues are often designed to mimic natural nucleotides but with modifications that can inhibit cellular processes, particularly rapid cell division characteristic of cancer. Researchers use this compound to test the efficacy and mechanisms of these potential new chemotherapy drugs. This allows for a deeper understanding of how these analogues interact with cellular enzymes and pathways.

For scientists engaged in chemotherapy research, having access to high-purity biochemical reagents is paramount. NINGBO INNO PHARMCHEM CO., LTD. understands these needs and provides 2'-Deoxyuridine 5'-monophosphate disodium salt with an assay of u226598.0% (HPLC). This ensures that experimental results are accurate and reproducible. Sourcing such critical materials from a trusted manufacturer in China like NINGBO INNO PHARMCHEM CO., LTD. can streamline the research process.

Researchers looking to buy this essential compound for their work in enzyme kinetics, drug discovery, or cancer research will find its consistent quality a significant advantage. The ability to purchase a reliable reference substrate for dTMP production directly supports progress in developing targeted cancer therapies.

In conclusion, 2'-Deoxyuridine 5'-monophosphate disodium salt is more than just a chemical compound; it's a key enabler of scientific discovery in the fight against cancer. Its application in studying thymidylate synthetase and dUMP analogues underscores its importance in the field of chemotherapy development. Researchers seeking to buy high-quality materials for their critical studies can rely on NINGBO INNO PHARMCHEM CO., LTD. for their supply needs.