Unveiling the Chemistry: Applications of 3-Bromo-5-fluoropyridin-2-amine
The world of organic chemistry thrives on the discovery and application of versatile molecular building blocks. Among these, 3-Bromo-5-fluoropyridin-2-amine, commonly known by its CAS number 869557-43-7, stands out due to its unique chemical structure and broad applicability, particularly in the pharmaceutical sector. This pyridine derivative, featuring strategically placed bromine, fluorine, and amino groups, offers a rich platform for complex chemical synthesis.
At its core, the utility of 3-Bromo-5-fluoropyridin-2-amine lies in its reactivity. The bromine atom serves as a leaving group, readily participating in cross-coupling reactions like Suzuki, Sonogashira, and Buchwald-Hartwig aminations, which are fundamental in constructing carbon-carbon and carbon-nitrogen bonds. The fluorine atom influences the electronic properties of the pyridine ring, potentially enhancing metabolic stability and target binding affinity in drug molecules. The amino group can be further functionalized or act as a directing group in regioselective reactions.
In pharmaceutical synthesis, this compound is indispensable for creating a wide array of heterocycles and complex organic molecules that form the basis of many active pharmaceutical ingredients (APIs). Researchers leverage its structure to design novel drug candidates targeting various therapeutic areas, from oncology to infectious diseases. When seeking to buy 3-Bromo-5-fluoropyridin-2-amine, it is crucial to source from manufacturers who guarantee high purity, often exceeding 99%, ensuring the integrity and efficiency of these complex synthetic routes.
Beyond pharmaceuticals, this intermediate finds use in materials science and agrochemical research. Its structural versatility allows for the development of functional materials with tailored properties. For academic and industrial researchers, having reliable access to this compound through trusted suppliers is key to pushing the boundaries of chemical innovation.
In conclusion, 3-Bromo-5-fluoropyridin-2-amine is a chemical workhorse with profound implications for various scientific disciplines. Its intrinsic reactivity makes it a valuable intermediate for synthesizing complex molecules. To support your research and development needs, prioritize sourcing this compound from reputable manufacturers and suppliers who can assure quality and consistent availability, enabling you to buy with confidence and achieve your scientific goals.
Perspectives & Insights
Logic Thinker AI
“The amino group can be further functionalized or act as a directing group in regioselective reactions.”
Molecule Spark 2025
“In pharmaceutical synthesis, this compound is indispensable for creating a wide array of heterocycles and complex organic molecules that form the basis of many active pharmaceutical ingredients (APIs).”
Alpha Pioneer 01
“Researchers leverage its structure to design novel drug candidates targeting various therapeutic areas, from oncology to infectious diseases.”