For professionals in chemical synthesis and pharmaceutical manufacturing, a deep understanding of the chemical intermediates they work with is fundamental. Valsartan, identified by its CAS number 137862-53-4, is a prime example of such a critical compound. As a key building block for important cardiovascular drugs, its chemical properties and optimal synthesis applications are of significant interest. This article provides an overview of Valsartan’s chemical profile and its utility, aimed at those looking to buy Valsartan pharmaceutical intermediate for their research or production needs.

Chemical Profile of Valsartan

Valsartan (C24H29N5O3) is characterized by its molecular weight of 435.52 g/mol. Typically supplied as a white crystalline powder, its physical form is crucial for handling and processing in synthesis reactions. Its solubility characteristics, melting point (around 116-117°C), and stability are all important parameters that a reliable Valsartan manufacturer will detail in their product specifications.

Understanding these properties is vital for:

  • Reaction Design: The solubility and stability influence solvent selection and reaction conditions.
  • Formulation Development: Physical properties like particle size and morphology can impact the downstream formulation of APIs.
  • Quality Control: Analytical methods like HPLC and NMR are used to verify purity and structural integrity, ensuring that the supplied Valsartan meets the required standards for synthesis.

Application in Pharmaceutical Synthesis

The primary application of Valsartan as a chemical intermediate is in the synthesis of Angiotensin II Receptor Blockers (ARBs). These drugs are essential for treating conditions such as hypertension and heart failure. The specific structure of Valsartan allows for targeted reactions that build upon its framework to create the final active pharmaceutical ingredient. Professionals seeking to source Valsartan CAS 137862-53-4 are often engaged in the development or large-scale production of these critical medications.

When procuring Valsartan, it is essential to partner with a Valsartan chemical supplier that can guarantee consistency in these chemical properties. A supplier that provides detailed analytical data for each batch, ensuring it meets established specifications, is indispensable for successful and compliant pharmaceutical manufacturing.

Choosing a Supplier for Your Synthesis Needs

For effective procurement, consider the following when selecting a Valsartan manufacturer in China or elsewhere:

  • Commitment to Quality: Prioritize suppliers with strong quality control systems and transparent documentation of chemical properties.
  • Technical Support: A supplier with technical expertise can provide valuable insights into handling and optimizing reactions involving Valsartan.
  • Reliable Supply: Ensure the supplier can consistently meet your volume requirements and delivery timelines.

By focusing on the chemical integrity and reliable sourcing of Valsartan, pharmaceutical manufacturers can ensure the quality and efficacy of their end products, contributing to better patient outcomes.