VEGFR-2 Inhibitors: The Role of 3-Bromo-5-methylbenzoic Acid in Cancer Therapy
The advancement of targeted cancer therapies has revolutionized how we approach disease treatment, focusing on specific molecular pathways that drive tumor growth. Among these, inhibitors of Vascular Endothelial Growth Factor Receptor-2 (VEGFR-2) have emerged as a crucial class of drugs, aiming to disrupt tumor angiogenesis. The synthesis of these sophisticated molecules often relies on specialized chemical intermediates, and 3-Bromo-5-methylbenzoic Acid (CAS: 58530-13-5) stands out as a vital component in this process.
The Chemical Profile of 3-Bromo-5-methylbenzoic Acid
3-Bromo-5-methylbenzoic Acid is an organic compound characterized by its pale yellow solid appearance. Its molecular formula, C8H7BrO2, and CAS number, 58530-13-5, identify it clearly within the chemical landscape. Its chemical structure, featuring a benzoic acid core with bromine and methyl substituents, provides reactive sites essential for complex synthesis. This compound's melting point typically falls between 178-179.5°C, indicative of its solid state under standard conditions.
Synthesis of VEGFR-2 Inhibitors
The primary application driving the demand for 3-Bromo-5-methylbenzoic Acid is its use as an intermediate in the synthesis of quinoline amide derivatives. These derivatives are engineered to act as potent VEGFR-2 inhibitors. By blocking VEGFR-2, these compounds prevent the formation of new blood vessels that tumors rely on for survival and growth. This mechanism is critical for slowing or halting tumor progression, making 3-Bromo-5-methylbenzoic Acid a cornerstone in the research and manufacturing of cutting-edge anti-cancer drugs.
For pharmaceutical developers and research chemists, ensuring a reliable supply of high-purity 3-Bromo-5-methylbenzoic Acid is non-negotiable. When you buy 3-bromo-5-methylbenzoic acid, you are securing a vital building block for therapeutic innovation. As a trusted manufacturer, we prioritize producing this intermediate to meet the stringent quality demands of the pharmaceutical sector. We encourage you to purchase 3-bromo-5-methylbenzoic acid from a reputable supplier that guarantees purity and consistency.
Procurement and Manufacturer Considerations
When sourcing 3-Bromo-5-methylbenzoic Acid, understanding the price of 3-bromo-5-methylbenzoic acid and the reliability of the manufacturer are key factors. Selecting a 3-bromo-5-methylbenzoic acid supplier in China or globally requires due diligence to ensure product quality and ethical sourcing practices. We are committed to being that trusted partner, providing high-quality intermediates for critical research and development projects. We welcome your inquiries for quotes and samples.
In conclusion, 3-Bromo-5-methylbenzoic Acid is a fundamental intermediate that enables the creation of advanced targeted therapies. Its role in synthesizing VEGFR-2 inhibitors highlights its significant contribution to the field of oncology and the broader pharmaceutical industry.
Perspectives & Insights
Alpha Spark Labs
“The synthesis of these sophisticated molecules often relies on specialized chemical intermediates, and 3-Bromo-5-methylbenzoic Acid (CAS: 58530-13-5) stands out as a vital component in this process.”
Future Pioneer 88
“The Chemical Profile of 3-Bromo-5-methylbenzoic Acid3-Bromo-5-methylbenzoic Acid is an organic compound characterized by its pale yellow solid appearance.”
Core Explorer Pro
“Its molecular formula, C8H7BrO2, and CAS number, 58530-13-5, identify it clearly within the chemical landscape.”