Venetoclax Synthesis: The Role of ABT-199 Intermediates
The development of targeted cancer therapies has revolutionized patient care, and Venetoclax stands as a prime example of this progress. Its synthesis relies on a series of complex chemical reactions, with specific intermediates playing pivotal roles. Among these, 3-Nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)benzenesulfonamide, also known as an ABT-199 intermediate (CAS 1228779-96-1), is critical. Understanding its function and sourcing reliably is key for pharmaceutical companies and research institutions.
Venetoclax, a potent BCL-2 inhibitor, has shown significant efficacy in treating certain types of leukemia and lymphoma. The chemical pathway to its creation involves assembling several molecular components, with intermediates like 3-Nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)benzenesulfonamide serving as essential building blocks. These intermediates must be synthesized with high precision and purity to ensure the final drug’s effectiveness and safety profile. NINGBO INNO PHARMCHEM CO.,LTD., a reputable chemical intermediate supplier in China, provides this vital compound, contributing to the efficient and reliable production of Venetoclax. We offer competitive pricing that supports cost-effective drug manufacturing.
Beyond its direct application in Venetoclax synthesis, this intermediate is also valuable in research related to other inhibitors targeting similar cellular pathways, such as BTK, PI3K, and JAK-2. This broad utility underscores the importance of having dependable access to high-quality chemical compounds. NINGBO INNO PHARMCHEM CO.,LTD. is committed to meeting these demands by providing not only competitive prices but also consistent product quality. When you choose to buy pharmaceutical intermediates from us, you are partnering with a manufacturer that understands the critical nature of your supply chain.
The global pharmaceutical market necessitates a strategic approach to sourcing raw materials and intermediates. Factors such as price, purity, lead time, and supplier reliability are crucial considerations. NINGBO INNO PHARMCHEM CO.,LTD. addresses these needs comprehensively. We are a leading manufacturer in China, offering 3-Nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)benzenesulfonamide at attractive price points, backed by a strong commitment to quality assurance and timely delivery. Our aim is to facilitate breakthroughs in medicine by ensuring researchers and manufacturers have the essential chemical components they need.
Perspectives & Insights
Data Seeker X
“Understanding its function and sourcing reliably is key for pharmaceutical companies and research institutions.”
Chem Reader AI
“Venetoclax, a potent BCL-2 inhibitor, has shown significant efficacy in treating certain types of leukemia and lymphoma.”
Agile Vision 2025
“The chemical pathway to its creation involves assembling several molecular components, with intermediates like 3-Nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)benzenesulfonamide serving as essential building blocks.”