Organic synthesis is the cornerstone of chemical innovation, enabling the creation of complex molecules that drive progress in pharmaceuticals, materials science, and beyond. Within this field, certain chemical intermediates emerge as particularly valuable due to their unique reactivity and structural versatility. 2-Amino-5-methoxybenzonitrile (CAS: 23842-82-2) is one such compound, offering chemists a powerful tool for constructing intricate molecular architectures.

Understanding the Chemical Profile

2-Amino-5-methoxybenzonitrile, with its IUPAC name 2-cyano-4-methoxyaniline, is characterized by its aromatic ring substituted with an amino group, a nitrile group, and a methoxy group. This combination of functional groups imparts a rich reactivity profile, making it an excellent starting material or intermediate for a wide range of organic transformations. Typically supplied as a pale yellow to dark beige solid, it has a moderate melting point of 46-47℃. Its molecular formula is C8H8N2O, and it is often available with purity levels of 97% or higher, ensuring its suitability for demanding synthetic applications.

Applications Across Chemical Disciplines

The utility of 2-Amino-5-methoxybenzonitrile extends across several domains of organic chemistry:

  • Heterocyclic Chemistry: The presence of both an amino and a nitrile group on the same aromatic ring makes it an ideal precursor for synthesizing various nitrogen-containing heterocycles. These structures are fundamental in medicinal chemistry and material science.
  • Pharmaceutical Intermediates: As mentioned previously, it's a key intermediate for pharmaceutical synthesis, facilitating the creation of complex molecules with potential therapeutic activities. Researchers looking to buy pharmaceutical intermediates often rely on compounds like this.
  • Agrochemical Intermediates: Similarly, its structure lends itself to the synthesis of active ingredients used in crop protection, contributing to the development of new pesticides and herbicides.
  • Dyes and Pigments: The compound can also serve as an intermediate in the production of specialty dyes and fluorescent brightening agents, where its chemical structure contributes to desired optical properties.

Sourcing High-Quality 2-Amino-5-methoxybenzonitrile

For organic chemists and procurement specialists, securing a reliable and high-quality source for 2-Amino-5-methoxybenzonitrile is paramount. Many leading chemical manufacturers, particularly those based in China, specialize in producing such intermediates. When you decide to purchase this compound, look for suppliers who provide comprehensive technical data, including Certificates of Analysis (CoA) detailing purity, as well as safe handling and storage guidelines. Companies that offer competitive pricing and a consistent supply chain are invaluable partners for ongoing research and development projects.

Whether you are synthesizing novel drug candidates, developing advanced agrochemicals, or exploring new material properties, 2-Amino-5-methoxybenzonitrile offers a valuable entry point into complex molecular structures. By partnering with a reputable chemical supplier, you can ensure that your synthesis projects are well-supported with this versatile and essential organic building block.