2-Bromoethyl ethyl ether, identified by CAS number 592-55-2, stands out as a highly versatile and indispensable intermediate in the realm of modern organic synthesis. Its unique molecular structure, featuring both an ether linkage and a reactive bromine atom, grants it significant utility across various industrial sectors, most notably in pharmaceuticals, agrochemicals, and the production of fine chemicals. Understanding its chemical properties and reactivity is crucial for chemists looking to optimize their synthesis pathways.

Chemical Profile and Physical Characteristics

As a colorless to brown transparent liquid, 2-Bromoethyl ethyl ether possesses a molecular formula of C4H9BrO and a molecular weight of approximately 153.02 g/mol. Key physical properties include a boiling point around 149-150°C and a density of 1.357 g/mL at 25°C. Its refractive index is typically reported around 1.445. While it is slightly soluble in water, it readily dissolves in common organic solvents, making it amenable to a wide range of reaction conditions. The presence of the bromine atom makes it an excellent electrophile, readily participating in nucleophilic substitution reactions.

Key Roles in Chemical Synthesis

The primary utility of 2-Bromoethyl ethyl ether lies in its function as an alkylating agent. It is extensively used to introduce the ethoxyethyl moiety into target molecules. This is particularly valuable in:

  • Pharmaceutical Intermediate Synthesis: It serves as a critical building block for synthesizing complex active pharmaceutical ingredients (APIs). The introduction of the ethoxyethyl group can modify solubility, bioavailability, and efficacy of drug candidates. Researchers often seek to buy this compound for advanced drug discovery programs.
  • Agrochemicals: In the agrochemical industry, it is employed in the synthesis of pesticides, herbicides, and other crop protection agents. Its structure can contribute to the biological activity and stability of these compounds.
  • Dyestuff and Specialty Chemicals: Its reactive nature also finds application in the creation of specialized dyes and other fine chemicals where the specific ether functionality is desired.
  • Precursor for Other Reagents: It can also be converted into other useful synthons, such as Grignard reagents, further expanding its synthetic potential.

For companies looking to purchase this vital intermediate, identifying a reliable manufacturer and supplier, especially one in China, is essential for ensuring consistent quality and cost-effectiveness. When sourcing, always inquire about purity levels (≥98.0% is common) and available packaging options to meet your laboratory or industrial scale needs.