In the realm of organic chemistry, specific building blocks are essential for constructing complex molecular architectures. 3-Iodophenol (CAS 626-02-8) stands out as a highly versatile compound, widely recognized for its utility in organic synthesis and various research applications. As a leading producer and supplier of fine chemicals, we are proud to offer high-purity 3-Iodophenol to researchers and industrial chemists worldwide.

What Makes 3-Iodophenol a Key Intermediate?

The chemical structure of 3-Iodophenol, characterized by an iodine substituent at the meta position relative to the hydroxyl group on a benzene ring, provides multiple reactive sites. This dual functionality allows chemists to perform a variety of transformations, including:

  • Cross-Coupling Reactions: The aryl iodide moiety is an excellent substrate for palladium-catalyzed cross-coupling reactions such as Suzuki, Heck, and Sonogashira couplings. These reactions are fundamental for forming new carbon-carbon bonds, enabling the synthesis of diverse aromatic compounds.
  • Nucleophilic Aromatic Substitution: The hydroxyl group can be modified or used as a directing group in further reactions. It can also be converted into other functional groups or participate in ether or ester formation.
  • Electrophilic Aromatic Substitution: The benzene ring itself can undergo electrophilic aromatic substitution, with the existing substituents influencing the regioselectivity of these reactions.

Applications in Research and Development

The versatility of 3-Iodophenol translates into its broad application across various scientific disciplines:

  • Drug Discovery: As a critical pharmaceutical intermediate, 3-Iodophenol is used to synthesize novel drug candidates and complex APIs. Its ability to participate in C-C bond formation is particularly valuable in building the carbon frameworks of many therapeutic agents.
  • Material Science: It can serve as a precursor for functional materials, polymers, or dyes where specific electronic or optical properties are desired, leveraging the presence of the iodine atom and phenolic group.
  • Agrochemicals: Similar to its use in pharmaceuticals, 3-Iodophenol can be employed as an intermediate in the synthesis of pesticides and herbicides, contributing to crop protection solutions.
  • Academic Research: For academic chemists, 3-Iodophenol is a staple reagent for exploring new synthetic methodologies, developing catalytic systems, and synthesizing target molecules for various scientific investigations.

Procuring 3-Iodophenol from a Reliable Source

When you need to buy 3-Iodophenol for your research or synthetic projects, sourcing from a reliable manufacturer like us is crucial. We ensure that our 3-Iodophenol (CAS 626-02-8) is of the highest quality, with guaranteed purity and consistent batch-to-batch reproducibility. Our efficient production processes and supply chain management allow us to offer competitive pricing, making this essential building block accessible for both small-scale laboratory use and larger industrial requirements. We encourage you to contact us for a quote and to discuss your specific project needs. Our team is ready to support your endeavors in organic synthesis and chemical innovation.