Hypromellose (HPMC), a derivative of cellulose, is a highly versatile excipient widely recognized for its utility in pharmaceutical formulations. While its roles in tablet film coating and as a binder are well-established, its applications extend far beyond these core functions. At NINGBO INNO PHARMCHEM CO.,LTD., we provide pharmaceutical-grade HPMC that enables formulators to tackle complex drug development challenges, offering competitive pricing and reliable supply from our China-based manufacturing facilities.

Taste Masking and Palatability Improvement:

Many active pharmaceutical ingredients (APIs) possess bitter or unpleasant tastes, which can significantly impact patient compliance, especially in pediatric or orally disintegrating dosage forms. HPMC can be used to coat drug particles or form a film around tablets to mask these undesirable flavors. The film-forming properties of HPMC create a barrier that prevents the drug from interacting with taste receptors in the mouth, leading to a more palatable product. Selecting the appropriate HPMC grade with good film integrity is crucial for effective taste masking.

Amorphous Solid Dispersions (ASDs):

Improving the solubility and bioavailability of poorly water-soluble drugs is a major challenge in pharmaceutical development. Amorphous Solid Dispersions (ASDs) are a promising strategy where the API is dispersed in a polymer matrix in an amorphous state. HPMC can serve as a carrier polymer in ASDs. When formulated correctly, HPMC helps to maintain the drug in its amorphous state, thereby enhancing its dissolution rate and subsequent absorption. Different HPMC grades can be utilized depending on the drug-polymer interactions and desired release characteristics.

Other Pharmaceutical Applications:

  • Pellet Coating: Similar to tablet coating, HPMC is used to coat pellets and granules, providing protection, controlled release, or taste masking.
  • Viscosity Modification: In liquid or semi-solid formulations like ophthalmic solutions or topical preparations, HPMC acts as a viscosity enhancer, improving the product's texture, spreadability, and residence time on the application site.
  • Excipient for Specialized Formulations: HPMC finds utility in various other specialized formulations, including orally dissolving films and as a component in powder formulations for reconstitution.

Your Trusted Partner for Pharmaceutical HPMC:

NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing the pharmaceutical industry with high-quality Hypromellose products. Our range of HPMC grades, manufactured to meet stringent pharmacopoeial standards, ensures you have the right material for your innovative formulations. As a leading supplier in China, we offer competitive pricing and a reliable supply chain, making us an ideal partner for your research and manufacturing needs.

Explore the extensive capabilities of Hypromellose in your pharmaceutical development. Contact us today to buy HPMC and discuss how our products can contribute to your formulation success.