The Versatility of Boronic Acids: Focus on 5-Bromo-2-fluorophenylboronic Acid
Boronic acids have emerged as indispensable tools in modern synthetic chemistry, prized for their stability, low toxicity, and remarkable reactivity, particularly in metal-catalyzed cross-coupling reactions. Among the diverse array of boronic acids available, 5-Bromo-2-fluorophenylboronic acid (CAS 112204-57-6) stands out for its unique structural features and broad applicability across various scientific disciplines. For businesses looking to purchase this compound, understanding its synthetic utility and reliable sourcing is crucial.
5-Bromo-2-fluorophenylboronic acid is a sophisticated organoboron compound characterized by a phenyl ring bearing bromine at the 5-position and fluorine at the 2-position, in addition to the functional boronic acid group. This specific substitution pattern enhances its electronic properties and reactivity, making it a preferred choice for demanding synthetic applications. Its primary role is as a coupling partner in Suzuki-Miyaura reactions, a Nobel Prize-winning methodology that efficiently forms carbon-carbon bonds. This makes it a vital building block for synthesizing complex organic molecules, including active pharmaceutical ingredients (APIs) and advanced materials.
The synthesis of 5-Bromo-2-fluorophenylboronic acid typically involves the borylation of 5-bromo-2-fluorobenzene, often employing reagents like bis(pinacolato)diboron in the presence of a palladium catalyst and a base. These methods are scalable for industrial production, allowing manufacturers like Ningbo Inno Pharmchem Co., Ltd. to offer this intermediate in significant quantities. As a dedicated manufacturer in China, we are committed to producing high-purity 5-Bromo-2-fluorophenylboronic acid, ensuring consistent quality for our B2B clients in the pharmaceutical, materials science, and fine chemical sectors.
The versatility of this compound is evident in its application in creating new therapeutic agents and developing novel electronic materials. For researchers and procurement specialists, sourcing such critical raw materials requires a partner who understands the technical demands and supply chain complexities. Ningbo Inno Pharmchem Co., Ltd. offers a robust solution, providing direct access to this essential chemical intermediate. We pride ourselves on our ability to meet the needs of businesses seeking reliable suppliers and competitive pricing for high-quality chemical products. If you need to buy 5-Bromo-2-fluorophenylboronic acid, consider our expertise and commitment to customer satisfaction.
We invite you to explore the potential of 5-Bromo-2-fluorophenylboronic acid in your next project. Contact Ningbo Inno Pharmchem Co., Ltd. today to discuss your requirements, request a quote, and learn more about how our manufacturing capabilities can support your innovation and production goals. Partner with us for dependable access to high-quality fine chemicals.
Perspectives & Insights
Future Origin 2025
“The synthesis of 5-Bromo-2-fluorophenylboronic acid typically involves the borylation of 5-bromo-2-fluorobenzene, often employing reagents like bis(pinacolato)diboron in the presence of a palladium catalyst and a base.”
Core Analyst 01
“These methods are scalable for industrial production, allowing manufacturers like Ningbo Inno Pharmchem Co.”
Silicon Seeker One
“As a dedicated manufacturer in China, we are committed to producing high-purity 5-Bromo-2-fluorophenylboronic acid, ensuring consistent quality for our B2B clients in the pharmaceutical, materials science, and fine chemical sectors.”