At NINGBO INNO PHARMCHEM CO.,LTD., we are dedicated to supplying essential pharmaceutical excipients that form the backbone of effective drug formulations. Today, we shine a light on starch, and more specifically, pregelatinized starch, as a cornerstone excipient in the pharmaceutical industry.

Starch, a natural polysaccharide, has long been utilized in pharmaceutical manufacturing. However, the advent of pregelatinized starch has revolutionized its application. This modified form of starch is produced through a process that gelatinizes the starch granules, making them soluble in cold water and enhancing their functional properties. This makes it an invaluable component when considering how to improve tablet integrity with starch.

Pregelatinized starch serves multiple critical functions within a tablet formulation. Primarily, it acts as an excellent tablet binder, imparting the necessary cohesiveness to powder blends, facilitating granulation, and ensuring the mechanical strength of the finished tablets. Its efficacy in this role contributes significantly to product stability and shelf life.

Equally important are its pregelatinized starch disintegrant properties. Upon contact with gastrointestinal fluids, the pregelatinized starch granules swell, causing the tablet to break apart rapidly. This facilitates a faster release of the active pharmaceutical ingredient (API), which is crucial for achieving optimal drug bioavailability and therapeutic efficacy.

Beyond binding and disintegration, pregelatinized starch is a cost effective excipient. Its versatility often allows for the reduction or elimination of other excipients, leading to more streamlined and economical formulations for oral solid dosage forms. This cost-effectiveness, combined with its functional benefits, makes it a highly attractive option for pharmaceutical manufacturers.

NINGBO INNO PHARMCHEM CO.,LTD. provides pharmaceutical-grade pregelatinized starch, ensuring consistent quality and performance. We empower formulators to create robust, efficient, and cost-effective medications by leveraging the diverse benefits of this essential pharmaceutical excipient.