In the vast landscape of organic chemistry, certain compounds stand out for their versatility and importance across multiple industries. 2,4-Difluorotoluene (CAS 452-76-6) is one such chemical intermediate, serving as a critical building block for pharmaceuticals, agrochemicals, and advanced materials like those used in OLED displays. For procurement managers and R&D scientists, understanding its properties and how to source it reliably is essential.

Understanding 2,4-Difluorotoluene: Properties and Specifications

2,4-Difluorotoluene, also known by its IUPAC name 2,4-difluoro-1-methylbenzene, is a fluorinated aromatic hydrocarbon. Key physical and chemical properties include:

  • Molecular Formula: C7H6F2
  • Molecular Weight: 128.12 g/mol
  • Appearance: Colorless transparent liquid
  • Purity: Typically available at ≥98% purity, verified by Gas Chromatography (GC). High purity is critical for its use in demanding synthesis applications.
  • Boiling Point: Approximately 113-117 °C (lit.).
  • Density: Around 1.12 g/mL at 25 °C (lit.).
  • Flash Point: Low, indicating flammability (e.g., 59 °F). Handle with appropriate safety precautions.

The defining characteristic is the presence of two fluorine atoms, which significantly influences its reactivity and the properties of compounds derived from it. This makes it a valuable intermediate for introducing fluorinated motifs into larger molecules.

Key Applications of 2,4-Difluorotoluene

The versatility of 2,4-Difluorotoluene is evident in its wide range of applications:

  • Pharmaceutical Intermediates: It is a crucial building block for synthesizing Active Pharmaceutical Ingredients (APIs), contributing to the development of drugs with improved efficacy, stability, and pharmacokinetic profiles.
  • Agrochemical Intermediates: Used in the creation of advanced pesticides, herbicides, and fungicides, where fluorination can enhance biological activity and environmental persistence.
  • OLED Intermediates: Serves as a precursor for molecules used in the fabrication of organic light-emitting diodes, contributing to improved display brightness, color purity, and operational lifetime.
  • Organic Synthesis: A general-purpose intermediate in various fine chemical synthesis projects requiring fluorinated aromatic compounds.

Where to Buy 2,4-Difluorotoluene: Partnering with Manufacturers

When seeking to buy 2,4-Difluorotoluene, it is essential to partner with reputable manufacturers and suppliers. For businesses, especially those in China, companies like NINGBO INNO PHARMCHEM CO.,LTD. offer high-quality products with consistent specifications. When procuring this chemical:

  • Verify Purity: Always request a Certificate of Analysis (CoA) confirming purity (e.g., ≥98% GC) and other critical parameters.
  • Check Specifications: Ensure the product meets your specific application requirements, such as low water content.
  • Compare Pricing: Obtain detailed quotes from multiple suppliers, but prioritize quality and reliability over the lowest price alone.
  • Assess Supplier Reputation: Look for suppliers with a proven track record in producing and delivering fine chemicals.

Engaging with established suppliers ensures you receive a product that meets international standards and supports your research and production goals effectively. Whether you are a research scientist or a procurement manager, understanding the importance of sourcing from dependable manufacturers in China for compounds like 2,4-Difluorotoluene is key to successful project outcomes.