In the vast landscape of organic chemistry, certain molecules stand out due to their versatility and importance as building blocks. 6-Methyl-2-pyridinecarboxaldehyde, identified by its CAS number 1122-72-1, is one such compound. This heterocylic aldehyde, often referred to by synonyms like 6-methylpicolinaldehyde or 2-formyl-6-methylpyridine, plays a crucial role in various synthetic processes within the chemical and pharmaceutical industries.

Chemical Identity and Properties

6-Methyl-2-pyridinecarboxaldehyde is an organic compound with the molecular formula C7H7NO and a molecular weight of approximately 121.14 g/mol. It is characterized by a pyridine ring substituted with a methyl group at the 6-position and an aldehyde group at the 2-position. Typically, it appears as a light yellow to brown low melting solid, with a melting point in the range of 31-33 °C. Its solubility in water is significant (750 g/L at 20 °C), and it is also soluble in organic solvents like ether and acetone. The compound is noted to be sensitive to light and air, requiring appropriate storage conditions, usually refrigerated (0-6°C or 2-8°C).

Key Applications and Uses

The dual functionality of the aldehyde group and the pyridine nucleus makes 6-Methyl-2-pyridinecarboxaldehyde a valuable intermediate in organic synthesis. Its primary applications include:

  • Pharmaceutical Synthesis: It serves as a key precursor in the synthesis of various pharmaceutical compounds. Researchers utilize it to build complex molecular structures that can exhibit therapeutic properties, such as anticonvulsant activities, by reacting it with different amines and other functional groups.
  • Diagnostic Reagent Formulation: The compound can be incorporated into the development of diagnostic reagents, where its reactivity is leveraged to create specific markers or indicators for biological assays.
  • Fine Chemical Manufacturing: It is used as a building block in the production of other fine chemicals and specialty materials.

Sourcing and Procurement

For researchers and manufacturers looking to buy 6-Methyl-2-pyridinecarboxaldehyde, understanding where to source it is important. Reputable chemical suppliers and manufacturers offer this compound, often with purity levels of 97% or 98%. When purchasing, it is beneficial to consider factors such as purity, availability, and price. Partnering with a reliable supplier, especially those experienced in exporting from countries like China, can ensure consistent quality and competitive pricing for your research or manufacturing needs.

Conclusion

6-Methyl-2-pyridinecarboxaldehyde (CAS 1122-72-1) is an essential organic intermediate with diverse applications. Its unique chemical structure and reactivity make it a valuable asset for synthetic chemists. Whether for advanced pharmaceutical development or the creation of precise diagnostic tools, understanding this compound’s properties and sourcing it from trusted chemical partners is key to success.