The relentless pursuit of novel molecules in the pharmaceutical and materials science sectors necessitates access to specialized chemical intermediates. Among these, boronic acids have gained immense importance, particularly in facilitating complex bond formations. 2,6-Difluoropyridine-3-boronic acid (CAS 136466-94-9) stands out as a versatile pyridine derivative, prized for its unique fluorination pattern and its utility as a coupling partner. For R&D scientists and procurement specialists, understanding where to buy 2,6-difluoropyridine-3-boronic acid with guaranteed high purity is a critical logistical challenge.

Chemical Profile and Reactivity

2,6-Difluoropyridine-3-boronic acid is typically supplied as a white powder, with purity levels often specified at ≥99%. This chemical intermediate features a difluorinated pyridine ring connected to a boronic acid group. This structural combination makes it exceptionally useful in palladium-catalyzed cross-coupling reactions, most notably the Suzuki-Miyaura coupling. Its reactivity allows for the efficient introduction of the 2,6-difluoropyridin-3-yl moiety into a wide array of organic molecules. The compound is soluble in water, facilitating its use in various reaction media.

Applications Driving Demand

The demand for 2,6-difluoropyridine-3-boronic acid stems from its significant role in several key industries:

  • Pharmaceutical Research: It serves as a vital building block for synthesizing drug candidates, particularly those where fluorine incorporation is desired to enhance pharmacokinetic properties or target binding.
  • Agrochemical Synthesis: Used in the development of new pesticides and herbicides, contributing to the efficiency and specificity of crop protection agents.
  • Materials Science: Explored for its potential in creating advanced organic materials with tailored electronic and optical characteristics.

When considering the price of 2,6-difluoropyridine-3-boronic acid, it is important to assess not only the per-gram cost but also the reliability of the supplier and the consistency of the product quality.

Finding Reliable Suppliers in China

China is a leading global source for specialty chemicals and intermediates. Companies seeking to secure a stable supply of 2,6-difluoropyridine-3-boronic acid often turn to Chinese manufacturers. NINGBO INNO PHARMCHEM CO.,LTD. is a distinguished 2,6-difluoropyridine-3-boronic acid manufacturer dedicated to providing high-purity products backed by robust quality assurance. When selecting a 2,6-difluoropyridine-3-boronic acid supplier, due diligence is essential. This includes verifying their production capabilities, obtaining Certificates of Analysis (COAs) for each batch, and ensuring clear communication channels for technical support and order fulfillment. By partnering with a reputable manufacturer, you can confidently purchase 2,6-difluoropyridine-3-boronic acid for your critical synthetic needs.

In summary, the strategic sourcing of high-purity 2,6-difluoropyridine-3-boronic acid from reliable manufacturers, particularly those in China, is key to advancing research and development in the pharmaceutical and chemical industries.