Procuring high-quality chemical reagents is a critical function for any research institution or pharmaceutical company. For those involved in peptide synthesis, sourcing Fmoc-Gly-OH (CAS 29022-11-5) requires careful consideration of supplier reliability, product purity, and overall cost-effectiveness. This article aims to guide procurement managers and R&D scientists in identifying and evaluating sources for this essential amino acid derivative.

The Role of Fmoc-Gly-OH in Modern Chemistry

Fmoc-Gly-OH is a cornerstone reagent in solid-phase peptide synthesis (SPPS). Its Fmoc (9-fluorenylmethyloxycarbonyl) protecting group allows for the sequential addition of amino acids under mild conditions, a process vital for building complex peptide sequences. As the simplest Fmoc-protected amino acid, Fmoc-Gly-OH is used in a vast array of peptide-based research and development projects, from therapeutic peptide discovery to biochemical tool development.

Key Factors When Buying Fmoc-Gly-OH

When you search to buy Fmoc-Gly-OH, several factors should guide your decision:

  • Purity and Specifications: Look for products with a minimum purity of 97%, often specified by HPLC or TLC. A Certificate of Analysis (CoA) from the manufacturer is essential for verifying these specifications.
  • Manufacturer vs. Distributor: While distributors can be convenient, purchasing directly from a manufacturer, especially one based in China with established expertise, can often lead to better pricing and direct technical support.
  • Supply Chain Reliability: For ongoing projects or production, securing a stable supply chain is crucial. Consider manufacturers with robust production capacities and inventory management.
  • Pricing and Volume Discounts: Manufacturers typically offer tiered pricing based on quantity. Requesting quotes for different batch sizes will help you secure the best price for your needs.
  • Technical Support: A responsive supplier who can provide technical data, handling advice, and answer specific questions about the product is invaluable.

Finding a Reputable Supplier

Identifying reliable manufacturers for Fmoc-Gly-OH (CAS 29022-11-5) often involves leveraging industry networks, online chemical directories, and trade show information. Companies specializing in pharmaceutical intermediates and amino acid derivatives are prime candidates. Many leading suppliers are located in China, offering competitive advantages in both cost and production scale. When evaluating potential suppliers, always inquire about their quality management systems (e.g., ISO certification) and their ability to provide consistent product quality batch after batch.

Investing in high-quality Fmoc-Gly-OH is an investment in the success of your peptide synthesis projects. By carefully selecting your supplier and prioritizing purity and reliability, you can ensure efficient progress and high-quality outcomes.