In the intricate world of pharmaceutical manufacturing and organic synthesis, the selection of high-quality intermediates is paramount. Among these, 5-Bromopyridine-2-carboxylic acid (CAS 30766-11-1) stands out as a particularly versatile and valuable compound. Its unique chemical structure, featuring a pyridine ring substituted with both a bromine atom and a carboxylic acid group, makes it an indispensable building block for a wide array of complex molecules. For procurement managers and R&D scientists seeking reliable suppliers, understanding the benefits and applications of this chemical is key to optimizing your sourcing strategy.

The Chemical Advantage: A Versatile Building Block

5-Bromopyridine-2-carboxylic acid is primarily sought after for its utility in various cross-coupling reactions, most notably the Suzuki-Miyaura and Buchwald-Hartwig couplings. These reactions are foundational in modern organic chemistry, allowing for the efficient formation of carbon-carbon and carbon-nitrogen bonds, respectively. The bromine atom at the 5-position of the pyridine ring acts as an excellent leaving group in these palladium-catalyzed processes, facilitating the introduction of diverse substituents. Simultaneously, the carboxylic acid group at the 2-position offers a reactive handle for further derivatization, such as esterification or amidation, enabling the synthesis of a broad spectrum of target molecules.

As a supplier of this critical intermediate, we emphasize its role in creating advanced pharmaceutical ingredients (APIs) and complex agrochemicals. Researchers in medicinal chemistry often utilize this compound to construct novel heterocyclic scaffolds that exhibit promising biological activities. Its consistent quality and availability as a white to off-white powder from reliable manufacturers in China ensure that your research and development pipelines remain robust and efficient. When considering where to buy, opting for a manufacturer with stringent quality control is crucial.

Sourcing Strategies for Procurement Professionals

For procurement managers, identifying a dependable manufacturer and supplier is a strategic imperative. The stability of supply, competitive pricing, and adherence to purity standards are non-negotiable. When searching for 5-Bromopyridine-2-carboxylic acid, consider suppliers that can provide comprehensive technical documentation, including Certificates of Analysis (CoA) and Material Safety Data Sheets (MSDS). The ability to request samples for evaluation before committing to bulk purchases is also a significant advantage. Engaging with manufacturers based in China often provides a strong value proposition due to efficient production capabilities and a well-established chemical industry infrastructure.

The price of 5-Bromopyridine-2-carboxylic acid can vary based on purity, quantity, and supplier. By directly contacting manufacturers, you can often secure more favorable pricing and ensure a stable supply chain, especially for larger orders. For instance, exploring options for bulk purchase or long-term supply agreements can lead to significant cost savings and mitigate supply chain risks.

In conclusion, 5-Bromopyridine-2-carboxylic acid is a cornerstone intermediate for many advanced chemical synthesis projects. By partnering with reputable manufacturers and suppliers, R&D scientists and procurement professionals can confidently source this essential compound, driving innovation in pharmaceutical and agrochemical development. We encourage you to contact us to discuss your specific requirements and to learn more about how we can support your chemical sourcing needs.