In the complex world of pharmaceutical manufacturing, the quality and availability of key intermediates are paramount. One such critical compound is Trans-4-Methylcyclohexylamine, identified by its CAS number 2523-55-9. This versatile amine serves as a foundational building block, most notably in the synthesis of Glimepiride, a widely prescribed medication for managing type 2 diabetes. For R&D scientists and procurement managers, understanding the sourcing and application of this chemical is key to ensuring efficient and cost-effective production.

Trans-4-Methylcyclohexylamine is characterized by its clear to pale yellow liquid appearance and possesses a distinct amine-like odor. With a molecular formula of C7H15N and a molecular weight of 113.20 g/mol, it exhibits specific physicochemical properties, including a boiling point around 149.3°C and a density close to 0.8 g/cm³. Its purity is a critical factor, with specifications typically requiring ≥98% or ≥99.0% (GC analysis) to meet the stringent demands of pharmaceutical synthesis. The chemical also carries hazard classifications, such as being flammable and corrosive, underscoring the need for careful handling and appropriate safety protocols during its use and storage.

The primary industrial application driving demand for Trans-4-Methylcyclohexylamine is its role as a direct precursor in the multi-step synthesis of Glimepiride. Glimepiride is a third-generation sulfonylurea drug that works by stimulating the pancreas to produce more insulin and increasing the sensitivity of peripheral tissues to insulin. The precise chemical structure of Trans-4-Methylcyclohexylamine makes it an indispensable component in forming the final active pharmaceutical ingredient (API). Therefore, securing a reliable supply of high-quality Trans-4-Methylcyclohexylamine is essential for any pharmaceutical company involved in Glimepiride production.

For businesses seeking to buy Trans-4-Methylcyclohexylamine, sourcing from established manufacturers and suppliers in China presents a strategic advantage. China has emerged as a global hub for chemical production, offering competitive pricing and a vast network of specialized manufacturers. NINGBO INNO PHARMCHEM CO.,LTD., for instance, acts as a dedicated pharmaceutical intermediates supplier, connecting clients with high-purity materials. When you look for a Trans-4-Methylcyclohexylamine manufacturer in China, prioritizing those with strong quality control, regulatory compliance, and a proven track record in supplying intermediates for API synthesis is crucial.

The benefits of partnering with a reputable Trans-4-Methylcyclohexylamine supplier extend beyond cost savings. It includes access to detailed technical documentation, such as Material Safety Data Sheets (MSDS) and Certificates of Analysis (CoA), ensuring product quality and safe usage. Furthermore, established suppliers can often accommodate customized packaging and delivery requirements, facilitating seamless integration into your manufacturing processes. By choosing the right supplier, you ensure not only the quality of your raw materials but also the reliability of your supply chain, a critical factor in meeting market demands for essential medicines like Glimepiride.

In summary, Trans-4-Methylcyclohexylamine (CAS 2523-55-9) is a cornerstone intermediate for Glimepiride production. Understanding its properties, applications, and the benefits of sourcing from leading Chinese manufacturers is vital for any pharmaceutical company aiming for operational excellence. For reliable access to this critical chemical, consider engaging with established suppliers who prioritize quality, consistency, and customer support to purchase Trans-4-Methylcyclohexylamine.