Understanding the molecular mechanisms underlying sensation and biological responses is crucial for advancing scientific knowledge and developing new products. WS-12 (CAS 68489-09-8) has garnered significant attention in scientific circles for its potent and selective agonism of the TRPM8 channel. As a specialized supplier of high-quality research chemicals, we provide access to WS-12 for researchers worldwide.

WS-12 functions by activating the TRPM8 channel, a protein that plays a critical role in sensing cold temperatures and compounds like menthol. This activation triggers a cascade of cellular events that are fundamental to our perception of cooling and pain. With a reported EC50 of 193 nM, WS-12 is considerably more potent than natural activators like menthol, making it an ideal compound for detailed in vitro studies. Its precise mechanism of action allows researchers to probe the structure-activity relationships of TRPM8 and explore its involvement in various physiological and pathological processes.

The applications of WS-12 extend beyond basic research. Its efficacy as a cooling agent is being explored in the flavor and fragrance industries, offering new avenues for product development. Furthermore, its role in TRPM8-related conditions, such as inflammatory pain and certain types of cancer, positions it as a valuable intermediate for pharmaceutical research. By partnering with a reliable manufacturer like us, you ensure access to a consistently pure supply of WS-12, which is essential for the validity of your scientific investigations.

For scientists and product developers, understanding the comprehensive profile of WS-12 is key. We offer detailed technical information and support, ensuring you have the knowledge needed to effectively utilize this compound. If you are looking to purchase WS-12, inquire about pricing, or learn more about its potential applications, please reach out to our team. We are committed to being your preferred supplier for advanced research chemicals, empowering your scientific endeavors with quality and reliability.