Z-GLN(TRT)-OH (CAS 132388-60-4): Applications in Pharmaceutical Research & Development
The journey of a new drug from concept to market is a complex and demanding process, heavily reliant on specialized chemical intermediates. Z-GLN(TRT)-OH (CAS 132388-60-4), a meticulously protected amino acid derivative, is a critical component in the arsenal of pharmaceutical researchers and developers. Its unique structure and chemical properties make it indispensable for various applications within drug discovery and development pipelines.
Understanding Z-GLN(TRT)-OH for Pharmaceutical Innovation
Z-GLN(TRT)-OH, known chemically as N-ALPHA-CARBOBENZOXY-N-GAMMA-TRITYL-L-GLUTAMINE, is a derivative of L-glutamine that features strategic protecting groups on its reactive sites. The carbobenzyloxy (Z) group safeguards the alpha-amino function, while the trityl (Trt) group protects the side-chain amide. This dual protection allows for precise control during peptide bond formation in both solid-phase and solution-phase peptide synthesis. Researchers can confidently incorporate glutamine residues, which are prevalent in many biologically active peptides, into their target molecules.
Key Applications in Pharmaceutical R&D
1. Peptide Therapeutics: Z-GLN(TRT)-OH is fundamental in synthesizing peptide-based drugs, which are increasingly important in treating a wide range of conditions, from metabolic disorders to cancer. Its use ensures the integrity and efficacy of these complex therapeutic peptides.
2. Drug Discovery: In the early stages of drug discovery, researchers synthesize libraries of peptide analogs to identify lead compounds. High-quality Z-GLN(TRT)-OH, available for purchase from reliable suppliers, accelerates this screening process.
3. Bioconjugation: Protected amino acids can be modified and used in bioconjugation strategies, linking peptides to other molecules like proteins, antibodies, or imaging agents to create targeted drug delivery systems or diagnostic tools.
4. Custom Synthesis Projects: For specialized research or the development of unique active pharmaceutical ingredients (APIs), Z-GLN(TRT)-OH serves as a versatile chiral building block in complex organic synthesis pathways.
Partnering with NINGBO INNO PHARMCHEM CO.,LTD.
NINGBO INNO PHARMCHEM CO.,LTD. stands as a leading manufacturer and supplier of Z-GLN(TRT)-OH CAS 132388-60-4 in China. We are committed to providing pharmaceutical R&D professionals with access to high-purity intermediates that meet rigorous quality standards. Our goal is to support your innovation by offering a stable supply chain and competitive pricing. We invite you to inquire about our products and secure your source for this essential pharmaceutical intermediate.
Perspectives & Insights
Future Origin 2025
“Z-GLN(TRT)-OH (CAS 132388-60-4), a meticulously protected amino acid derivative, is a critical component in the arsenal of pharmaceutical researchers and developers.”
Core Analyst 01
“Its unique structure and chemical properties make it indispensable for various applications within drug discovery and development pipelines.”
Silicon Seeker One
“Understanding Z-GLN(TRT)-OH for Pharmaceutical Innovation Z-GLN(TRT)-OH, known chemically as N-ALPHA-CARBOBENZOXY-N-GAMMA-TRITYL-L-GLUTAMINE, is a derivative of L-glutamine that features strategic protecting groups on its reactive sites.”