For research scientists and formulation experts, a deep understanding of a chemical's properties and synthesis is crucial for its effective application. Methyl 2-acetylamino-3-chloropropionate (CAS 18635-38-6) is a fine chemical intermediate that plays a significant role in various industrial sectors, most notably in the production of electronic chemicals and as a building block in organic synthesis. This article delves into its key chemical characteristics and common synthetic pathways.

Methyl 2-acetylamino-3-chloropropionate, with the molecular formula C6H10ClNO3 and a molecular weight of 179.60, is typically found as a white solid. Its physical properties, such as a melting point ranging from 74-76°C, indicate its solid state under ambient conditions. Solubility in common organic solvents like dichloromethane, ethyl acetate, and methanol makes it amenable to various reaction conditions and purification techniques. Several synonyms are associated with this compound, including N-acetylmine-3-chloro-L-alaninemethyl ester and Methyl 2-acetylamino-3-chloropropanoate, reflecting its structural relationships.

From a synthesis perspective, this compound can be prepared through acetylation reactions. A common method involves reacting (R)-methyl 2-amino-3-chloropropionate with acetic anhydride under controlled temperature conditions, often in an inert solvent like diethyl ether. The reaction proceeds to form the desired N-acetylated product, which is then isolated and purified. This synthesis highlights the importance of precursors like amino acid derivatives and acetylation agents, readily available from reliable chemical suppliers.

The structure of Methyl 2-acetylamino-3-chloropropionate, featuring a chiral center, an ester group, a chlorine atom, and an amide linkage, makes it a versatile intermediate. These functional groups can be selectively manipulated in subsequent reactions, allowing for the construction of more complex molecules. For researchers looking to buy this chemical for their projects, understanding these properties aids in designing efficient synthetic strategies and optimizing experimental parameters.

As a key player in the fine chemical industry, NINGBO INNO PHARMCHEM CO.,LTD. ensures that Methyl 2-acetylamino-3-chloropropionate is produced to exacting standards. Whether you are involved in developing new photoresist technologies or exploring novel organic compounds, reliable access to high-quality intermediates like this is paramount. We invite you to connect with us to purchase this chemical, discuss its applications, and leverage our expertise as a leading manufacturer and supplier.