For chemists and researchers in both academic and industrial settings, a deep understanding of chemical intermediates is foundational to successful synthesis projects. 2-Chloromandelic Acid (CAS 10421-85-9) is one such compound that merits attention due to its versatility and utility in various chemical transformations. This article aims to provide a comprehensive overview of its key properties and common applications, helping procurement managers and R&D scientists make informed decisions when looking to buy this essential chemical.

Chemical Identity and Physical Properties

2-Chloromandelic Acid, identified by CAS Number 10421-85-9, is chemically known as Benzeneacetic acid, 2-chloro-α-hydroxy-. Its molecular formula is C8H7ClO3, with a corresponding molecular weight of 186.59 g/mol. Typically, this compound presents as a white to pale cream crystalline powder. While detailed information on its melting and boiling points can vary slightly between sources, it is generally recognized as a stable solid under standard laboratory conditions. Its solubility characteristics are also important for synthetic chemists, influencing reaction solvent choices.

Key Applications in Chemical Synthesis

The primary applications for 2-Chloromandelic Acid lie in its role as a versatile intermediate. It is extensively used in:

  • Photoresist Chemicals: In the electronics industry, it serves as a precursor for specialized chemicals used in the formulation of photoresists. These materials are crucial for photolithography, enabling the high-precision patterning required for semiconductor manufacturing.
  • Pharmaceutical Intermediates: The compound is a valuable chiral building block for the synthesis of a wide array of pharmaceutical molecules. Its structure allows for the introduction of specific stereochemical configurations into drug candidates, contributing to their efficacy and safety.
  • Fine Chemical Synthesis: Beyond these major sectors, 2-Chloromandelic Acid is employed in the broader synthesis of fine chemicals, where its unique functionalities can be exploited for various organic transformations.

Sourcing and Procurement Advice

For R&D scientists and purchasing managers, sourcing high-quality 2-Chloromandelic Acid is crucial. When considering where to buy, it is important to look for suppliers who can guarantee product purity (often specified as >95% by HPLC) and provide comprehensive documentation such as Certificates of Analysis (CoA). As a manufacturer and supplier based in China, we are equipped to meet these demands, offering competitive pricing for this essential chemical intermediate. We understand the importance of a reliable supply chain for both research quantities and larger industrial orders. Engaging with experienced manufacturers ensures not only product quality but also adherence to safety and handling protocols.

Conclusion

2-Chloromandelic Acid is a testament to the intricate nature of chemical synthesis and its impact on modern technology and medicine. Its well-defined properties and diverse applications make it a sought-after intermediate. For those in the market to purchase this compound, focusing on reliable suppliers who can provide documented quality and consistent availability will pave the way for successful research and production outcomes.