In the dynamic field of material science, stimuli-responsive polymers have garnered significant attention for their ability to adapt to environmental changes. Among these, N-Isopropylacrylamide (NIPAM) stands out as a crucial monomer, particularly for the development of thermo-responsive hydrogels. As a leading chemical manufacturer and supplier, understanding the capabilities of NIPAM is key for researchers and product developers.

N-Isopropylacrylamide, identified by its CAS number 2210-25-5, is an acrylamide derivative characterized by a unique molecular structure. It features a hydrophilic amide group and a hydrophobic isopropyl group. This dual nature is responsible for its most prominent characteristic: the lower critical solution temperature (LCST). When NIPAM-based polymers are dissolved in water and heated above their LCST, which is typically around 33°C, they undergo a dramatic change. The polymer chains collapse, leading to a significant volume phase transition and a decrease in solubility. This behavior makes NIPAM an invaluable building block for creating “smart” materials that respond predictably to temperature fluctuations.

The primary application for NIPAM lies in the synthesis of poly(N-isopropylacrylamide) (pNIPAM) and its copolymers. These polymers form hydrogels that can swell or shrink in response to temperature changes. Such thermo-responsive hydrogels are highly sought after in various advanced applications. For instance, in the pharmaceutical industry, they are used for controlled drug release systems. A drug encapsulated within a pNIPAM hydrogel can be released as the hydrogel shrinks at a specific temperature, offering precise therapeutic delivery.

Beyond pharmaceuticals, NIPAM-based materials are finding significant use in tissue engineering and regenerative medicine. The biocompatibility of pNIPAM makes it suitable for creating scaffolds that support cell growth and differentiation. These smart hydrogels can mimic the extracellular matrix and respond to physiological temperature changes, potentially aiding in tissue repair and regeneration. Researchers are also exploring their use in biomedical coatings for implants and medical devices, where their responsive nature can offer advantages in biocompatibility and functionality.

As a dedicated supplier and manufacturer of N-Isopropylacrylamide, we understand the importance of purity and consistency. For procurement managers and R&D scientists looking to buy N-Isopropylacrylamide, ensuring a reliable source is paramount. Our commitment is to provide high-quality NIPAM, enabling you to achieve reproducible results in your polymer synthesis and application development. We facilitate the purchase of N-Isopropylacrylamide for various research and industrial needs, offering competitive pricing and robust supply chain management.

The synthesis of N-Isopropylacrylamide typically involves reacting acryloyl chloride with isopropylamine. The quality of the starting materials and the reaction conditions are critical to achieving the desired purity. As a professional N-Isopropylacrylamide manufacturer in China, we employ stringent quality control measures throughout our production process. This ensures that the NIPAM we supply meets the high standards required for sensitive applications.

For those interested in exploring the potential of these smart materials, sourcing high-grade N-Isopropylacrylamide is the first step. Whether your project involves advanced drug delivery systems, novel biomaterials, or specialized coatings, NIPAM offers a unique property profile. We encourage you to reach out to us to inquire about our N-Isopropylacrylamide price and to discuss how we can meet your bulk purchasing needs. Partner with a trusted N-Isopropylacrylamide supplier to drive your next groundbreaking innovation.