Understanding D-Panthenol (CAS 81-13-0): Properties & Applications
D-Panthenol, chemically known as (2R)-2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutanamide and identified by CAS number 81-13-0, is a compound of significant interest across multiple industries, particularly cosmetics and pharmaceuticals. As the alcohol analog of pantothenic acid (Vitamin B5), it serves as a provitamin, readily converting to its active form within the body. This conversion underpins its efficacy as a moisturizing, healing, and conditioning agent. This article provides a comprehensive overview of D-Panthenol's key properties and applications, essential information for any professional seeking to buy this versatile ingredient.
Physical and Chemical Properties:
D-Panthenol is typically encountered as a colorless to faintly yellow, viscous liquid. Its molecular formula is C9H19NO4, with a molecular weight of approximately 205.25 g/mol. Key properties often specified by manufacturers and sought by buyers include its density (around 1.2 g/mL at 20 °C), refractive index (typically 1.495-1.502), and solubility. It is freely soluble in water, alcohol, and propylene glycol, making it highly amenable to incorporation into a wide range of formulations, from aqueous solutions to emulsions.
Moisturizing and Emollient Action:
One of D-Panthenol's most celebrated attributes is its ability to act as a potent humectant and emollient. When applied topically, it penetrates the skin and hair shaft, drawing moisture to the area and locking it in. This deeply hydrating effect improves skin elasticity, softness, and hair manageability. For formulators, this translates into superior performance in moisturizers, lotions, serums, shampoos, and conditioners. Sourcing cosmetic grade D-Panthenol from a reliable manufacturer ensures these benefits are consistently delivered.
Wound Healing and Anti-inflammatory Benefits:
Beyond its cosmetic appeal, D-Panthenol is recognized for its therapeutic properties. It plays a role in promoting epithelial cell proliferation and aiding in the repair of skin tissues. This makes it a valuable ingredient in products designed for wound care, burn treatments, and the management of various dermatological conditions such as eczema and dermatitis. Buyers looking for a pharmaceutical intermediate with proven healing capabilities will find D-Panthenol to be an excellent choice. Procurement of D-Panthenol for these applications necessitates adherence to strict purity standards.
Hair and Nail Conditioning:
In haircare, D-Panthenol is known to strengthen hair, increase its resistance to breakage, and provide long-lasting moisture. It coats the hair shaft, smoothing the cuticle and adding shine without a heavy feel. Similarly, it can penetrate the nail plate, improving flexibility and reducing brittleness. This dual action makes it a key ingredient in comprehensive beauty formulations.
Sourcing D-Panthenol:
When looking to purchase D-Panthenol, it is crucial to partner with reputable suppliers and manufacturers. Companies offering D-Panthenol in bulk, such as those in China, can provide competitive pricing for large orders. Key considerations for buyers include the CAS number (81-13-0), molecular specifications, and confirmation of the grade (e.g., cosmetic, USP/FCC). Ensuring a stable supply chain from a trusted manufacturer is vital for consistent product quality and business continuity.
In conclusion, D-Panthenol's unique combination of moisturizing, healing, and conditioning properties makes it an indispensable ingredient. Its broad applicability across diverse industries underscores its value, making it a smart choice for any formulator or procurement specialist.
Perspectives & Insights
Nano Explorer 01
“Sourcing D-Panthenol:When looking to purchase D-Panthenol, it is crucial to partner with reputable suppliers and manufacturers.”
Data Catalyst One
“Companies offering D-Panthenol in bulk, such as those in China, can provide competitive pricing for large orders.”
Chem Thinker Labs
“Key considerations for buyers include the CAS number (81-13-0), molecular specifications, and confirmation of the grade (e.”