Calcium Hydroxide has been a foundational material in dental pulp therapy for decades, offering a unique combination of antimicrobial activity and osteogenic potential. Its primary roles in this field are as a direct or indirect pulp capping agent and as a key component in apexification procedures. This article explores the efficacy of Calcium Hydroxide in these dental pulp therapies, highlighting its mechanisms of action and clinical outcomes.

In pulp capping, the goal is to preserve the vitality of the dental pulp following exposure due to caries, trauma, or iatrogenic injury. When applied directly to exposed pulp, Calcium Hydroxide creates a mild inflammatory response. This irritation, combined with its high pH, stimulates the differentiation of undifferentiated mesenchymal cells into odontoblasts. These newly formed odontoblasts then deposit a layer of reparative dentin, often referred to as a dentin bridge. This bridge acts as a natural barrier, protecting the underlying pulp tissue from further insults and allowing for healing. The efficacy of this process is well-documented, making Calcium Hydroxide a preferred material for direct pulp capping.

For indirect pulp capping, where the pulp is not directly exposed but is very close to the surface, Calcium Hydroxide is placed over the remaining dentin. Here, it continues to exert a mild antibacterial effect on residual microorganisms in the dentinal tubules and stimulates the formation of reparative dentin from the pulp. This approach aims to prevent pulp exposure, thus avoiding the need for more extensive treatments.

Apexification is another area where Calcium Hydroxide demonstrates significant efficacy. This treatment is indicated for immature teeth with necrotic pulps and open apices. The lack of a fully formed root apex compromises the tooth's structural integrity and its ability to withstand functional forces. Calcium Hydroxide is placed within the root canal as an intracanal medicament. Its prolonged contact with the periapical tissues encourages the deposition of calcified material at the apical end, gradually leading to the formation of an apical barrier. This process, while often requiring multiple applications over several months, is highly effective in achieving root-end closure, enabling subsequent root canal obturation and preserving the tooth.

The efficacy of Calcium Hydroxide in these therapeutic applications stems from its ability to create a favorable biological environment for tissue regeneration and repair. Its antimicrobial properties ensure a clean operative field, while its osteogenic potential drives the formation of vital hard tissues. NINGBO INNO PHARMCHEM CO.,LTD. supplies high-quality Calcium Hydroxide that meets the rigorous demands of dental pulp therapy, contributing to successful and long-lasting patient outcomes.