Understanding the Chemical Properties and Synthesis of Triclocarban
For researchers and product developers in the chemical and pharmaceutical industries, a deep understanding of a compound's chemical properties and synthesis is fundamental to its effective application. Triclocarban (TCC), a compound with significant antimicrobial activity, is no exception. This article provides an overview of TCC's chemical characteristics and common synthesis pathways, offering valuable insights for R&D scientists and procurement professionals.
Triclocarban, chemically known as N-(4-chlorophenyl)-N′-(3,4-dichlorophenyl)urea, has the molecular formula C13H9Cl3N2O and a molar mass of approximately 315.58 g/mol. It typically appears as a white powder with a high melting point, generally in the range of 250-255u00b0C. Its low solubility in water is a notable characteristic, influencing its formulation and application methods. The compound's structure features three chlorine atoms attached to two phenyl rings linked by a urea group, contributing to its lipophilicity and antimicrobial efficacy.
The synthesis of Triclocarban generally involves the reaction of isocyanates with amines. Two primary commercial routes are employed: the reaction of 4-chlorophenylisocyanate with 3,4-dichloroaniline, or the reaction of 3,4-dichlorophenylisocyanate with 4-chloroaniline. Both pathways yield the urea linkage characteristic of TCC. Manufacturers typically achieve a purity level of u226598% for commercial-grade Triclocarban, ensuring its suitability for various applications, from personal care products to industrial preservatives.
As a supplier, understanding these chemical nuances is crucial for assisting customers. For instance, the low water solubility of Triclocarban powder means it often requires specific formulation techniques, such as dispersion or incorporation into oil-based systems or emulsifiable concentrates, for optimal performance. When seeking to buy Triclocarban, customers often inquire about its stability under different conditions and its compatibility with other formulation ingredients.
The high purity (u226598%) of Triclocarban is a key specification for many end-users, especially in applications where precise dosing and consistent performance are critical. Manufacturers strive to maintain these high standards, offering TCC at competitive prices to facilitate its widespread adoption. Whether for industrial water treatment, coatings preservation, or other uses, the chemical integrity of the supplied Triclocarban directly impacts the final product's efficacy.
For researchers, understanding the synthesis of TCC also opens avenues for potential modification or the development of analogs with altered properties. However, for most industrial applications, sourcing high-quality, synthetically derived Triclocarban from a reputable manufacturer is the most practical approach. Companies that specialize in chemical manufacturing and supply, like ourselves, provide the necessary assurance of quality and consistency for this vital antibacterial agent.
In conclusion, Triclocarban's chemical properties and synthesis pathways are integral to its effectiveness as an antimicrobial agent. A thorough understanding of these aspects, coupled with reliable sourcing from experienced manufacturers, empowers R&D scientists and procurement professionals to leverage TCC’s capabilities effectively.
Perspectives & Insights
Quantum Pioneer 24
“The compound's structure features three chlorine atoms attached to two phenyl rings linked by a urea group, contributing to its lipophilicity and antimicrobial efficacy.”
Bio Explorer X
“The synthesis of Triclocarban generally involves the reaction of isocyanates with amines.”
Nano Catalyst AI
“Two primary commercial routes are employed: the reaction of 4-chlorophenylisocyanate with 3,4-dichloroaniline, or the reaction of 3,4-dichlorophenylisocyanate with 4-chloroaniline.”