ZIF-90 as a Drug Carrier: Advancing Pharmaceutical Delivery Systems
The field of drug delivery is continuously seeking innovative materials that can enhance therapeutic efficacy, improve patient compliance, and reduce side effects. Metal-Organic Frameworks (MOFs), with their tunable pore sizes and high loading capacities, are emerging as powerful candidates. Among them, ZIF-90 (CAS: 1062147-37-8) is gaining attention as a superior drug carrier. As a leading supplier of specialty chemicals in China, we are proud to offer high-purity ZIF-90 for pharmaceutical research and development.
The Pharmaceutical Potential of ZIF-90
ZIF-90's suitability as a drug carrier lies in its unique combination of physical and chemical properties:
- High Drug Loading Capacity: The extensive internal surface area (1500 m²/g) and pore volume (0.4 cm³/g) allow for significant amounts of active pharmaceutical ingredients (APIs) to be encapsulated within the framework.
- Controlled Release: The framework can be designed to degrade under specific environmental conditions found in the body, such as pH changes in the stomach or enzymes, leading to precise and controlled release of the loaded drug. This property is key for targeted therapies and reducing systemic exposure.
- Biocompatibility Considerations: While MOFs are an active area of research, ZIF-90's components (zinc and imidazole-2-carboxaldehyde) are generally considered less toxic than some heavy metals used in other nanomaterials, making it a promising candidate for further study in biocompatibility and biodistribution.
- Stability and Processing: ZIF-90’s stability in air and alkaline environments, coupled with its powder form, facilitates its processing and formulation into drug delivery systems. Activation at 100°C in a vacuum is recommended before use for optimal performance.
Applications in Drug Delivery
The potential applications of ZIF-90 in pharmaceutical science are diverse:
- Oral Drug Delivery: Its ability to degrade in the acidic environment of the stomach makes it ideal for delivering drugs orally, protecting them from degradation in the upper digestive tract and releasing them in the intestine. If you are developing advanced oral drug formulations, consider the benefits of purchasing ZIF-90.
- Targeted Therapy: By functionalizing the MOF surface or controlling its degradation rate, ZIF-90 can be engineered for targeted delivery to specific cells or tissues, minimizing off-target effects.
- Combination Therapy: The framework's capacity can be utilized to carry multiple drugs simultaneously, enabling synergistic therapeutic effects.
Partnering with a Trusted ZIF-90 Supplier in China
For pharmaceutical companies and research institutions, acquiring reliable, high-quality ZIF-90 is essential for successful drug development. We are a premier chemical manufacturer and supplier based in China, dedicated to providing materials with a minimum purity of 97%. Our commitment to quality ensures that the ZIF-90 you purchase will meet the rigorous demands of pharmaceutical research. We encourage you to inquire about our competitive price for ZIF-90 and to request a free sample. By choosing us as your ZIF-90 supplier, you gain access to an advanced material backed by expert manufacturing and a commitment to customer satisfaction. Buying ZIF-90 from our facility means partnering for innovation in pharmaceutical delivery.
Key Considerations for Pharmaceutical Buyers:
- Prioritize ZIF-90 suppliers with proven quality control and detailed characterization data.
- Evaluate the specific particle size and activation requirements for your drug delivery formulation.
- Engage with manufacturers for bulk supply and to discuss potential custom modifications.
ZIF-90 represents a significant advancement in the field of drug delivery, and by sourcing it from a dependable Chinese manufacturer, your R&D efforts can move forward with confidence.
Perspectives & Insights
Agile Reader One
“ZIF-90 represents a significant advancement in the field of drug delivery, and by sourcing it from a dependable Chinese manufacturer, your R&D efforts can move forward with confidence.”
Logic Vision Labs
“The field of drug delivery is continuously seeking innovative materials that can enhance therapeutic efficacy, improve patient compliance, and reduce side effects.”
Molecule Origin 88
“Metal-Organic Frameworks (MOFs), with their tunable pore sizes and high loading capacities, are emerging as powerful candidates.”