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Novel Grignard-based route for Apremilast intermediates ensures high purity and reduced waste, offering supply chain stability for pharmaceutical manufacturing partners.
Patent CN104447443B reveals a green Mannich route for Apremilast. Achieve high optical purity and significant cost reduction in pharmaceutical intermediates manufacturing with scalable processes.
Patent CN104447445A details a novel route for apremilast intermediate ensuring high purity and scalable manufacturing for global supply chains.