N-Fmoc-L-Threoninol Bulk Price 2026 Global Manufacturer
- High Purity Supply: Guaranteed industrial purity exceeding 99% for critical peptide coupling applications.
- 2026 Pricing Trends: Competitive bulk price tiers available for kilogram and ton-scale procurement.
- Global Compliance: Full documentation including COA, SDS, and COO adhering to GMP standards.
In the evolving landscape of medicinal chemistry and peptide engineering, securing a reliable supply chain for key building blocks is paramount. N-Fmoc-L-threoninol (CAS: 176380-53-3) stands as a critical intermediate for the synthesis of complex peptidomimetics and glycopeptides. As we approach 2026, global demand for this chiral amino alcohol derivative is projected to rise, driven by advancements in drug development and bioconjugation technologies. For procurement managers and chief scientific officers, understanding the technical specifications and commercial dynamics of this compound is essential for maintaining production continuity.
As a premier global manufacturer, NINGBO INNO PHARMCHEM CO.,LTD. is committed to delivering consistent quality and scalable supply solutions. This analysis details the technical attributes, pricing structures, and logistical capabilities required for industrial-scale acquisition of Fmoc-Thr-ol.
Technical Specifications and Synthesis Overview
The chemical integrity of (2R,3R)-Fmoc-Threoninol is defined by its specific stereochemistry, which is crucial for downstream reaction yields. With a molecular weight of 327.38 g/mole and a molecular formula of C19H21NO4, this compound functions as a protected amino alcohol. The 9H-fluoren-9-ylmethyl carbamate protecting group ensures stability during various synthetic transformations while allowing for selective deprotection under mild basic conditions.
Achieving high industrial purity requires a robust synthesis route that minimizes impurities such as diastereomers or unreacted starting materials. In large-scale production, controlling the reduction of the corresponding threonine derivative is vital. Buyers should prioritize suppliers who can provide detailed technical data regarding the manufacturing process to ensure batch-to-batch consistency. Impurities at even low levels can significantly impact peptide coupling efficiency, leading to costly delays in drug development pipelines.
Key physical and chemical properties include:
- CAS Number: 176380-53-3
- Appearance: White to off-white crystalline powder
- Solubility: Soluble in organic solvents such as DMF and DCM
- Storage: Store under inert gas at 2-8°C to prevent degradation
Wholesale Pricing Tiers and Volume Discounts
The market for peptide building blocks is sensitive to raw material costs and production scale. While small-scale research quantities often command premium pricing per gram, industrial procurement operates on a different economic model. The bulk price for Fmoc-L-Threoninol in 2026 is expected to stabilize as production capacities expand among top-tier manufacturers.
Procurement strategies should account for volume tiers. Small laboratory packs (1g to 25g) are suitable for initial screening but are economically inefficient for process development. Transitioning to kilogram-scale orders typically unlocks significant cost reductions. NINGBO INNO PHARMCHEM CO.,LTD. offers structured pricing models that reflect these economies of scale, ensuring that large-volume clients receive competitive rates without compromising on quality assurance.
The following table outlines the typical relationship between order volume and commercial terms:
| Order Volume | Target Application | Commercial Terms |
|---|---|---|
| Gram Scale (1g - 100g) | Research & Analytical Testing | Standard Catalog Pricing |
| Kilogram Scale (1kg - 10kg) | Process Development & Pilot Runs | Volume Discount Applied |
| Ton Scale (100kg+) | Commercial Manufacturing | Custom Contract Pricing |
Global Logistics and Lead Time Estimates
Reliable supply chains are the backbone of pharmaceutical manufacturing. Lead times can vary significantly depending on stock availability and custom synthesis requirements. For standard inventory items, shipment typically occurs within 5 to 7 business days following order confirmation. However, for large-scale bulk orders requiring specific packaging or additional quality testing, lead times may extend to 3-4 weeks.
Global logistics capabilities ensure that materials reach laboratories and production facilities worldwide without regulatory hindrance. Proper documentation is critical for customs clearance. Every shipment is accompanied by a comprehensive Safety Data Sheet (SDS) and a Product Specification (PS) document. These files provide essential information on handling, storage, and disposal, ensuring compliance with local safety regulations regardless of the destination.
Quality Assurance and Documentation
In the pharmaceutical industry, documentation is as valuable as the product itself. A valid COA (Certificate of Analysis) is mandatory for every batch released. This document verifies critical parameters such as purity, optical rotation, and residual solvent levels. For clients operating under strict regulatory frameworks, adherence to GMP standards is non-negotiable.
Our quality control protocols include:
- HPLC Analysis: Verification of purity levels exceeding 99.0%.
- Chiral HPLC: Confirmation of enantiomeric excess to ensure stereochemical integrity.
- Residual Solvent Testing: Compliance with ICH Q3C guidelines.
- Certificates of Origin (COO): Provided to facilitate trade compliance and customs processing.
Access to batch-specific records allows for full traceability. Clients can request historical data for audit purposes, ensuring that the N-Fmoc-L-threoninol supplied meets all predefined specifications. This level of transparency mitigates risk during regulatory filings and clinical trial material production.
Request Custom Quote for Industrial Scale
Securing a stable supply of high-performance peptide building blocks requires a partnership with a manufacturer capable of scaling alongside your needs. Whether for academic research, process optimization, or commercial drug production, having access to consistent quality materials is vital. The market landscape in 2026 favors buyers who establish long-term contracts with verified producers.
For inquiries regarding current stock levels, custom packaging requirements, or specific technical data sheets, our sales team is prepared to assist. We encourage potential partners to request a formal quotation based on their projected annual usage. By aligning procurement strategies with production schedules, companies can optimize inventory costs and ensure uninterrupted operations.
Contact us today to discuss your requirements for Fmoc-L-Threoninol and discover how our global supply network can support your scientific objectives.